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Chronic hyperinsulinemia promotes human hepatocyte senescence.
Baboota RK, Spinelli R, Erlandsson MC, Brandao BB, Lino M, Yang H, Mardinoglu A, Bokarewa MI, Boucher J, Kahn CR, Smith U. Baboota RK, et al. Mol Metab. 2022 Oct;64:101558. doi: 10.1016/j.molmet.2022.101558. Epub 2022 Jul 21. Mol Metab. 2022. PMID: 35872305 Free PMC article.
Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH.
Bonnet L, Alexandersson I, Baboota RK, Kroon T, Oscarsson J, Smith U, Boucher J. Bonnet L, et al. Among authors: baboota rk. Front Endocrinol (Lausanne). 2022 Aug 22;13:957616. doi: 10.3389/fendo.2022.957616. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36072934 Free PMC article.
Functional peroxisomes are required for β-cell integrity in mice.
Baboota RK, Shinde AB, Lemaire K, Fransen M, Vinckier S, Van Veldhoven PP, Schuit F, Baes M. Baboota RK, et al. Mol Metab. 2019 Apr;22:71-83. doi: 10.1016/j.molmet.2019.02.001. Epub 2019 Feb 8. Mol Metab. 2019. PMID: 30795913 Free PMC article.
Co-supplementation of isomalto-oligosaccharides potentiates metabolic health benefits of polyphenol-rich cranberry extract in high fat diet-fed mice via enhanced gut butyrate production.
Singh DP, Singh S, Bijalwan V, Kumar V, Khare P, Baboota RK, Singh P, Boparai RK, Singh J, Kondepudi KK, Chopra K, Bishnoi M. Singh DP, et al. Among authors: baboota rk. Eur J Nutr. 2018 Dec;57(8):2897-2911. doi: 10.1007/s00394-017-1561-5. Epub 2017 Nov 10. Eur J Nutr. 2018. PMID: 29127476
Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites.
Shinde AB, Baboota RK, Denis S, Loizides-Mangold U, Peeters A, Espeel M, Malheiro AR, Riezman H, Vinckier S, Vaz FM, Brites P, Ferdinandusse S, Van Veldhoven PP, Baes M. Shinde AB, et al. Among authors: baboota rk. Mitochondrion. 2018 Mar;39:51-59. doi: 10.1016/j.mito.2017.08.013. Epub 2017 Sep 1. Mitochondrion. 2018. PMID: 28866057
20 results