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A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation.
Pasqualon T, Pruessmeyer J, Weidenfeld S, Babendreyer A, Groth E, Schumacher J, Schwarz N, Denecke B, Jahr H, Zimmermann P, Dreymueller D, Ludwig A. Pasqualon T, et al. Among authors: babendreyer a. Cell Mol Life Sci. 2015 Oct;72(19):3783-801. doi: 10.1007/s00018-015-1912-4. Epub 2015 Apr 26. Cell Mol Life Sci. 2015. PMID: 25912030
A cytoplasmic C-terminal fragment of Syndecan-1 is generated by sequential proteolysis and antagonizes Syndecan-1 dependent lung tumor cell migration.
Pasqualon T, Pruessmeyer J, Jankowski V, Babendreyer A, Groth E, Schumacher J, Koenen A, Weidenfeld S, Schwarz N, Denecke B, Jahr H, Dreymueller D, Jankowski J, Ludwig A. Pasqualon T, et al. Among authors: babendreyer a. Oncotarget. 2015 Oct 13;6(31):31295-312. doi: 10.18632/oncotarget.5174. Oncotarget. 2015. PMID: 26378057 Free PMC article.
The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion.
Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, Deupi X, Ludwig A, Dreymueller D. Koenen A, et al. Among authors: babendreyer a. PLoS One. 2017 Mar 7;12(3):e0173486. doi: 10.1371/journal.pone.0173486. eCollection 2017. PLoS One. 2017. PMID: 28267793 Free PMC article.
Status update on iRhom and ADAM17: It's still complicated.
Düsterhöft S, Babendreyer A, Giese AA, Flasshove C, Ludwig A. Düsterhöft S, et al. Among authors: babendreyer a. Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1567-1583. doi: 10.1016/j.bbamcr.2019.06.017. Epub 2019 Jul 19. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 31330158 Free article. Review.
26 results