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Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.
Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, Yang F, Lo JW, Alberts E, Sa ACC, Niazi U, Friedman J, Long AK, Ding Y, Carey CD, Lamb C, Saqi M, Madgwick M, Gul L, Treveil A, Korcsmaros T, Macdonald TT, Lord GM, Bewick G, Powell N. Pavlidis P, et al. Nat Commun. 2022 Oct 3;13(1):5820. doi: 10.1038/s41467-022-33331-8. Nat Commun. 2022. PMID: 36192482 Free PMC article.
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Brooks-Warburton J, Modos D, Sudhakar P, Madgwick M, Thomas JP, Bohar B, Fazekas D, Zoufir A, Kapuy O, Szalay-Beko M, Verstockt B, Hall LJ, Watson A, Tremelling M, Parkes M, Vermeire S, Bender A, Carding SR, Korcsmaros T. Brooks-Warburton J, et al. Nat Commun. 2022 Apr 28;13(1):2299. doi: 10.1038/s41467-022-29998-8. Nat Commun. 2022. PMID: 35484353 Free PMC article.
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks.
Csabai L, Fazekas D, Kadlecsik T, Szalay-Bekő M, Bohár B, Madgwick M, Módos D, Ölbei M, Gul L, Sudhakar P, Kubisch J, Oyeyemi OJ, Liska O, Ari E, Hotzi B, Billes VA, Molnár E, Földvári-Nagy L, Csályi K, Demeter A, Pápai N, Koltai M, Varga M, Lenti K, Farkas IJ, Türei D, Csermely P, Vellai T, Korcsmáros T. Csabai L, et al. Nucleic Acids Res. 2022 Jan 7;50(D1):D701-D709. doi: 10.1093/nar/gkab909. Nucleic Acids Res. 2022. PMID: 34634810 Free PMC article.
Big data in IBD: big progress for clinical practice.
Seyed Tabib NS, Madgwick M, Sudhakar P, Verstockt B, Korcsmaros T, Vermeire S. Seyed Tabib NS, et al. Gut. 2020 Aug;69(8):1520-1532. doi: 10.1136/gutjnl-2019-320065. Epub 2020 Feb 28. Gut. 2020. PMID: 32111636 Free PMC article. Review.