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Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell Rep. 2022 Nov 1;41(5):111580. doi: 10.1016/j.celrep.2022.111580.
Cell Rep. 2022.
PMID: 36323248
Free PMC article.
Sacsin, mutated in the ataxia ARSACS, regulates intermediate filament assembly and dynamics.
Gentil BJ, Lai GT, Menade M, Larivière R, Minotti S, Gehring K, Chapple JP, Brais B, Durham HD.
Gentil BJ, et al.
FASEB J. 2019 Feb;33(2):2982-2994. doi: 10.1096/fj.201801556R. Epub 2018 Oct 17.
FASEB J. 2019.
PMID: 30332300
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