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2020 | 2 |
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The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun. 2021 Jun 23;12(1):3883. doi: 10.1038/s41467-021-24199-1.
Nat Commun. 2021.
PMID: 34162887
Free PMC article.
Evolution of DNA replication origin specification and gene silencing mechanisms.
Hu Y, Tareen A, Sheu YJ, Ireland WT, Speck C, Li H, Joshua-Tor L, Kinney JB, Stillman B.
Hu Y, et al.
Nat Commun. 2020 Oct 14;11(1):5175. doi: 10.1038/s41467-020-18964-x.
Nat Commun. 2020.
PMID: 33056978
Free PMC article.
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Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Yuan Z, Schneider S, Dodd T, Riera A, Bai L, Yan C, Magdalou I, Ivanov I, Stillman B, Li H, Speck C.
Yuan Z, et al.
Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17747-17756. doi: 10.1073/pnas.2006231117. Epub 2020 Jul 15.
Proc Natl Acad Sci U S A. 2020.
PMID: 32669428
Free PMC article.
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Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.
Noguchi Y, Yuan Z, Bai L, Schneider S, Zhao G, Stillman B, Speck C, Li H.
Noguchi Y, et al.
Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9529-E9538. doi: 10.1073/pnas.1712537114. Epub 2017 Oct 25.
Proc Natl Acad Sci U S A. 2017.
PMID: 29078375
Free PMC article.
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