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The autophagy-NAD axis in longevity and disease.
Wilson N, Kataura T, Korsgen ME, Sun C, Sarkar S, Korolchuk VI. Wilson N, et al. Trends Cell Biol. 2023 Sep;33(9):788-802. doi: 10.1016/j.tcb.2023.02.004. Epub 2023 Mar 5. Trends Cell Biol. 2023. PMID: 36878731 Free article. Review.
NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy.
Kataura T, Otten EG, Rabanal-Ruiz Y, Adriaenssens E, Urselli F, Scialo F, Fan L, Smith GR, Dawson WM, Chen X, Yue WW, Bronowska AK, Carroll B, Martens S, Lazarou M, Korolchuk VI. Kataura T, et al. EMBO J. 2023 Mar 1;42(5):e111372. doi: 10.15252/embj.2022111372. Epub 2022 Dec 14. EMBO J. 2023. PMID: 36514953 Free PMC article.
A Mammalian Target of Rapamycin-Perilipin 3 (mTORC1-Plin3) Pathway is essential to Activate Lipophagy and Protects Against Hepatosteatosis.
Garcia-Macia M, Santos-Ledo A, Leslie J, Paish HL, Collins AL, Scott RS, Watson A, Burgoyne RA, White S, French J, Hammond J, Borthwick LA, Mann J, Bolaños JP, Korolchuk VI, Oakley F, Mann DA. Garcia-Macia M, et al. Hepatology. 2021 Dec;74(6):3441-3459. doi: 10.1002/hep.32048. Epub 2021 Sep 21. Hepatology. 2021. PMID: 34233024 Free article.
Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Palmer AK, et al. Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25. Aging Cell. 2019. PMID: 30907060 Free PMC article.