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Page 1
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Nowak RP, Tumber A, Hendrix E, Ansari MSZ, Sabatino M, Antonini L, Andrijes R, Salah E, Mautone N, Pellegrini FR, Simelis K, Kawamura A, Johansson C, Passeri D, Pellicciari R, Ciogli A, Del Bufalo D, Ragno R, Coleman ML, Trisciuoglio D, Mai A, Oppermann U, Schofield CJ, Rotili D. Nowak RP, et al. J Med Chem. 2021 Dec 9;64(23):17031-17050. doi: 10.1021/acs.jmedchem.1c00605. Epub 2021 Nov 29. J Med Chem. 2021. PMID: 34843649 Free PMC article.
Inhibition of JMJD6 by 2-Oxoglutarate Mimics.
Islam MS, Thinnes CC, Holt-Martyn JP, Chowdhury R, McDonough MA, Schofield CJ. Islam MS, et al. ChemMedChem. 2022 Jan 5;17(1):e202100398. doi: 10.1002/cmdc.202100398. Epub 2021 Nov 16. ChemMedChem. 2022. PMID: 34581506 Free PMC article.
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Figg WD Jr, McDonough MA, Chowdhury R, Nakashima Y, Zhang Z, Holt-Martyn JP, Krajnc A, Schofield CJ. Figg WD Jr, et al. ChemMedChem. 2021 Jul 6;16(13):2082-2088. doi: 10.1002/cmdc.202100133. Epub 2021 Apr 9. ChemMedChem. 2021. PMID: 33792169 Free PMC article.
A human protein hydroxylase that accepts D-residues.
Choi H, Hardy AP, Leissing TM, Chowdhury R, Nakashima Y, Ge W, Markoulides M, Scotti JS, Gerken PA, Thorbjornsrud H, Kang D, Hong S, Lee J, McDonough MA, Park H, Schofield CJ. Choi H, et al. Commun Chem. 2020 May 1;3(1):52. doi: 10.1038/s42004-020-0290-5. Commun Chem. 2020. PMID: 36703414 Free PMC article.
36 results