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Year | Number of Results |
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2014 | 1 |
2016 | 1 |
2017 | 1 |
2019 | 1 |
2020 | 2 |
2024 | 0 |
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Page 1
Evolutionary Ecology and Interplay of Prokaryotic Innate and Adaptive Immune Systems.
Curr Biol. 2020 Oct 5;30(19):R1189-R1202. doi: 10.1016/j.cub.2020.08.028.
Curr Biol. 2020.
PMID: 33022264
Free PMC article.
Review.
5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage.
Mullally G, van Aelst K, Naqvi MM, Diffin FM, Karvelis T, Gasiunas G, Siksnys V, Szczelkun MD.
Mullally G, et al.
Nucleic Acids Res. 2020 Jul 9;48(12):6811-6823. doi: 10.1093/nar/gkaa477.
Nucleic Acids Res. 2020.
PMID: 32496535
Free PMC article.
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The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a.
van Aelst K, Martínez-Santiago CJ, Cross SJ, Szczelkun MD.
van Aelst K, et al.
Genes (Basel). 2019 Feb 22;10(2):169. doi: 10.3390/genes10020169.
Genes (Basel). 2019.
PMID: 30813348
Free PMC article.
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Single-Molecule Insight Into Target Recognition by CRISPR-Cas Complexes.
Rutkauskas M, Krivoy A, Szczelkun MD, Rouillon C, Seidel R.
Rutkauskas M, et al.
Methods Enzymol. 2017;582:239-273. doi: 10.1016/bs.mie.2016.10.001. Epub 2016 Dec 5.
Methods Enzymol. 2017.
PMID: 28062037
Free article.
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Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.
Szczelkun MD, Tikhomirova MS, Sinkunas T, Gasiunas G, Karvelis T, Pschera P, Siksnys V, Seidel R.
Szczelkun MD, et al.
Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9798-803. doi: 10.1073/pnas.1402597111. Epub 2014 May 27.
Proc Natl Acad Sci U S A. 2014.
PMID: 24912165
Free PMC article.
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