BB/H020527/2/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2010	1
2012	1
2013	1
2014	2
2015	2
2016	2
2017	2
2019	1
2022	2
2023	1
2024	0

1

Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice.

Ang SJ, Crombie EM, Dong H, Tan KT, Hernando A, Yu D, Adamson S, Kim S, Withers DJ, Huang H, Tsai SY. Ang SJ, et al. Nat Commun. 2022 Dec 17;13(1):7792. doi: 10.1038/s41467-022-35547-0. Nat Commun. 2022. PMID: 36526657 Free PMC article.

2

Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity.

Crombie EM, Kim S, Adamson S, Dong H, Lu TC, Wu Y, Wu Y, Levy Y, Stimple N, Lam WMR, Hey HWD, Withers DJ, Hsu AL, Bay BH, Ochala J, Tsai SY. Crombie EM, et al. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):198-213. doi: 10.1002/jcsm.13121. Epub 2022 Nov 17. J Cachexia Sarcopenia Muscle. 2023. PMID: 36398408 Free PMC article.

3

Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington's disease.

Irvine EE, Katsouri L, Plattner F, Al-Qassab H, Al-Nackkash R, Bates GP, Withers DJ. Irvine EE, et al. Sci Rep. 2019 Nov 6;9(1):16133. doi: 10.1038/s41598-019-52391-3. Sci Rep. 2019. PMID: 31695068 Free PMC article.

4

Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins.

Liao CY, Anderson SS, Chicoine NH, Mayfield JR, Garrett BJ, Kwok CS, Academia EC, Hsu YM, Miller DM, Bair AM, Wilson JA, Tannady G, Stewart EM, Adamson SS, Wang J, Withers DJ, Kennedy BK. Liao CY, et al. Cell Discov. 2017 Oct 31;3:17039. doi: 10.1038/celldisc.2017.39. eCollection 2017. Cell Discov. 2017. PMID: 29736257 Free PMC article.

5

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.

Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, Fisher FM, Pissios P, Withers DJ, Selman C, Wang R, Yen K, Longo VD, Cohen P, Bartke A, Kopchick JJ, Miller R, Hollenberg AN, Mitchell JR. Hine C, et al. Cell Metab. 2017 Jun 6;25(6):1320-1333.e5. doi: 10.1016/j.cmet.2017.05.003. Cell Metab. 2017. PMID: 28591635 Free PMC article.

6

Evidence that hematopoietic stem cell function is preserved during aging in long-lived S6K1 mutant mice.

Selman C, Sinclair A, Pedroni SM, Irvine EE, Michie AM, Withers DJ. Selman C, et al. Oncotarget. 2016 May 24;7(21):29937-43. doi: 10.18632/oncotarget.8729. Oncotarget. 2016. PMID: 27083004 Free PMC article.

7

Ageing: Out with the old.

Gil J, Withers DJ. Gil J, et al. Nature. 2016 Feb 11;530(7589):164-5. doi: 10.1038/nature16875. Epub 2016 Feb 3. Nature. 2016. PMID: 26840486 Free PMC article. No abstract available.

8

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.

Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Nat Cell Biol. 2015 Sep;17(9):1205-17. doi: 10.1038/ncb3225. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280535 Free PMC article.

9

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice.

Smith MA, Katsouri L, Irvine EE, Hankir MK, Pedroni SM, Voshol PJ, Gordon MW, Choudhury AI, Woods A, Vidal-Puig A, Carling D, Withers DJ. Smith MA, et al. Cell Rep. 2015 Apr 21;11(3):335-43. doi: 10.1016/j.celrep.2015.03.029. Epub 2015 Apr 9. Cell Rep. 2015. PMID: 25865886 Free PMC article.

10

Fibroblasts derived from long-lived insulin receptor substrate 1 null mice are not resistant to multiple forms of stress.

Page MM, Sinclair A, Robb EL, Stuart JA, Withers DJ, Selman C. Page MM, et al. Aging Cell. 2014 Oct;13(5):962-4. doi: 10.1111/acel.12255. Epub 2014 Jul 24. Aging Cell. 2014. PMID: 25059507 Free PMC article.

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