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ClosTron-targeted mutagenesis.
Heap JT, Cartman ST, Kuehne SA, Cooksley C, Minton NP. Heap JT, et al. Methods Mol Biol. 2010;646:165-82. doi: 10.1007/978-1-60327-365-7_11. Methods Mol Biol. 2010. PMID: 20597009
The emergence of 'hypervirulence' in Clostridium difficile.
Cartman ST, Heap JT, Kuehne SA, Cockayne A, Minton NP. Cartman ST, et al. Int J Med Microbiol. 2010 Aug;300(6):387-95. doi: 10.1016/j.ijmm.2010.04.008. Epub 2010 May 23. Int J Med Microbiol. 2010. PMID: 20547099 Review.
The ClosTron: Mutagenesis in Clostridium refined and streamlined.
Heap JT, Kuehne SA, Ehsaan M, Cartman ST, Cooksley CM, Scott JC, Minton NP. Heap JT, et al. J Microbiol Methods. 2010 Jan;80(1):49-55. doi: 10.1016/j.mimet.2009.10.018. Epub 2009 Nov 3. J Microbiol Methods. 2010. PMID: 19891996
A modular system for Clostridium shuttle plasmids.
Heap JT, Pennington OJ, Cartman ST, Minton NP. Heap JT, et al. J Microbiol Methods. 2009 Jul;78(1):79-85. doi: 10.1016/j.mimet.2009.05.004. Epub 2009 May 13. J Microbiol Methods. 2009. PMID: 19445976
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes.
Sebaihia M, Peck MW, Minton NP, Thomson NR, Holden MT, Mitchell WJ, Carter AT, Bentley SD, Mason DR, Crossman L, Paul CJ, Ivens A, Wells-Bennik MH, Davis IJ, Cerdeño-Tárraga AM, Churcher C, Quail MA, Chillingworth T, Feltwell T, Fraser A, Goodhead I, Hance Z, Jagels K, Larke N, Maddison M, Moule S, Mungall K, Norbertczak H, Rabbinowitsch E, Sanders M, Simmonds M, White B, Whithead S, Parkhill J. Sebaihia M, et al. Genome Res. 2007 Jul;17(7):1082-92. doi: 10.1101/gr.6282807. Epub 2007 May 22. Genome Res. 2007. PMID: 17519437 Free PMC article.