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2013 2
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Page 1
Synthesis of Chiral 1,2-Amino Alcohol-Containing Compounds Utilizing Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of Unprotected α-Ketoamines.
Mangunuru HPR, Terrab L, Janganati V, Kalikinidi NR, Tenneti S, Natarajan V, Shada ADR, Naini SR, Gajula P, Lee D, Samankumara LP, Mamunooru M, Jayaraman A, Sahani RL, Yin J, Hewa-Rahinduwage CC, Gangu A, Chen A, Wang Z, Desai B, Yue TY, Wannere CS, Armstrong JD 3rd, Donsbach KO, Sirasani G, Gupton BF, Qu B, Senanayake CH. Mangunuru HPR, et al. Among authors: gupton bf. J Org Chem. 2024 May 3;89(9):6085-6099. doi: 10.1021/acs.joc.4c00045. Epub 2024 Apr 22. J Org Chem. 2024. PMID: 38648720
Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline.
Robey JMS, Maity S, Aleshire SL, Ghosh A, Yadaw AK, Roy S, Mear SJ, Jamison TF, Sirasani G, Senanayake CH, Stringham RW, Gupton BF, Donsbach KO, Nelson RC, Shanahan CS. Robey JMS, et al. Among authors: gupton bf. Org Process Res Dev. 2023 Oct 13;27(11):2146-2159. doi: 10.1021/acs.oprd.3c00287. eCollection 2023 Nov 17. Org Process Res Dev. 2023. PMID: 38025988 Free PMC article.
Development of a Practical Synthesis of the 8-FDC Fragment of OPC-167832.
Gopalsamuthiram V, Ho DB, Peck CL, Natarajan V, Agrawal T, Burns JM, Bachert J, Cook DW, Stringham RW, Nelson R, Ahmad S, Gupton BF, Snead DR, McQuade DT, Vaidyanathan R, Donsbach K, Sieber JD. Gopalsamuthiram V, et al. Among authors: gupton bf. ACS Omega. 2022 Feb 18;7(8):7223-7228. doi: 10.1021/acsomega.1c06996. eCollection 2022 Mar 1. ACS Omega. 2022. PMID: 35252712 Free PMC article.
Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir.
Roy S, Yadaw A, Roy S, Sirasani G, Gangu A, Brown JD, Armstrong JD 3rd, Stringham RW, Gupton BF, Senanayake CH, Snead DR. Roy S, et al. Among authors: gupton bf. Org Process Res Dev. 2022 Jan 21;26(1):82-90. doi: 10.1021/acs.oprd.1c00071. Epub 2022 Jan 7. Org Process Res Dev. 2022. PMID: 35095258 Free PMC article. Review.
Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis.
Gopalsamuthiram V, Kadam AL, Noble JK, Snead DR, Williams C, Jamison TF, Senanayake C, Yadaw AK, Roy S, Sirasani G, Gupton BF, Burns J, Cook DW, Stringham RW, Ahmad S, Krack R. Gopalsamuthiram V, et al. Among authors: gupton bf. Org Process Res Dev. 2021 Dec 17;25(12):2679-2685. doi: 10.1021/acs.oprd.1c00219. Epub 2021 Dec 9. Org Process Res Dev. 2021. PMID: 34955627 Free PMC article. Review.
29 results