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Identification of the Privileged Position in the Imidazo[1,2-a]pyridine Ring of Phosphonocarboxylates for Development of Rab Geranylgeranyl Transferase (RGGT) Inhibitors.
Kaźmierczak A, Kusy D, Niinivehmas SP, Gmach J, Joachimiak Ł, Pentikäinen OT, Gendaszewska-Darmach E, Błażewska KM. Kaźmierczak A, et al. Among authors: blazewska km. J Med Chem. 2017 Nov 9;60(21):8781-8800. doi: 10.1021/acs.jmedchem.7b00811. Epub 2017 Oct 17. J Med Chem. 2017. PMID: 28953373
Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
Gendaszewska-Darmach E, Garstka MA, Błażewska KM. Gendaszewska-Darmach E, et al. Among authors: blazewska km. J Med Chem. 2021 Jul 22;64(14):9677-9710. doi: 10.1021/acs.jmedchem.1c00410. Epub 2021 Jul 8. J Med Chem. 2021. PMID: 34236862 Free PMC article. Review.
Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase.
Małolepsza J, Marchwicka A, Serwa RA, Niinivehmas SP, Pentikäinen OT, Gendaszewska-Darmach E, Błażewska KM. Małolepsza J, et al. Among authors: blazewska km. J Enzyme Inhib Med Chem. 2022 Dec;37(1):940-951. doi: 10.1080/14756366.2022.2053525. J Enzyme Inhib Med Chem. 2022. PMID: 35354390 Free PMC article.
Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT.
Coxon FP, Joachimiak L, Najumudeen AK, Breen G, Gmach J, Oetken-Lindholm C, Way R, Dunford JE, Abankwa D, Błażewska KM. Coxon FP, et al. Among authors: blazewska km. Eur J Med Chem. 2014 Sep 12;84:77-89. doi: 10.1016/j.ejmech.2014.06.062. Epub 2014 Jun 28. Eur J Med Chem. 2014. PMID: 25016230
27 results