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Strategies To Design Selective Histone Deacetylase Inhibitors.
Melesina J, Simoben CV, Praetorius L, Bülbül EF, Robaa D, Sippl W. Melesina J, et al. Among authors: bulbul ef. ChemMedChem. 2021 May 6;16(9):1336-1359. doi: 10.1002/cmdc.202000934. Epub 2021 Feb 19. ChemMedChem. 2021. PMID: 33428327 Review.
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
Ibrahim HS, Abdelsalam M, Zeyn Y, Zessin M, Mustafa AM, Fischer MA, Zeyen P, Sun P, Bülbül EF, Vecchio A, Erdmann F, Schmidt M, Robaa D, Barinka C, Romier C, Schutkowski M, Krämer OH, Sippl W. Ibrahim HS, et al. Among authors: bulbul ef. Int J Mol Sci. 2021 Dec 29;23(1):369. doi: 10.3390/ijms23010369. Int J Mol Sci. 2021. PMID: 35008795 Free PMC article.
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.
Sun P, Wang J, Khan KS, Yang W, Ng BW, Ilment N, Zessin M, Bülbül EF, Robaa D, Erdmann F, Schmidt M, Romier C, Schutkowski M, Cheng AS, Sippl W. Sun P, et al. Among authors: bulbul ef. J Med Chem. 2022 Dec 22;65(24):16313-16337. doi: 10.1021/acs.jmedchem.2c01132. Epub 2022 Nov 30. J Med Chem. 2022. PMID: 36449385
Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors.
Wimmer S, Hoff K, Martin B, Grewer M, Denni L, Lascorz Massanet R, Raimondi MV, Bülbül EF, Melesina J, Hotop SK, Haupenthal J, Rohde H, Heisig P, Hirsch AKH, Brönstrup M, Sippl W, Holl R. Wimmer S, et al. Among authors: bulbul ef. Bioorg Chem. 2023 Feb;131:106331. doi: 10.1016/j.bioorg.2022.106331. Epub 2022 Dec 19. Bioorg Chem. 2023. PMID: 36587505
13 results