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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators; Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, Londo… See abstract for full author list ➔ Demenais F, et al. Among authors: bonnelykke k. Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22. Nat Genet. 2018. PMID: 29273806 Free PMC article.
Age dependent systemic exposure to inhaled salbutamol.
Bønnelykke K, Jespersen JJ, Bisgaard H. Bønnelykke K, et al. Br J Clin Pharmacol. 2007 Aug;64(2):241-4. doi: 10.1111/j.1365-2125.2007.02868.x. Epub 2007 Mar 1. Br J Clin Pharmacol. 2007. PMID: 17335545 Free PMC article. Clinical Trial.
Extrapolating evidence beyond age groups.
Bisgaard H, Bønnelykke K. Bisgaard H, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2008 Apr;121(4):1066-7; author reply 1067-8. doi: 10.1016/j.jaci.2008.01.068. Epub 2008 Mar 5. J Allergy Clin Immunol. 2008. PMID: 18325574 No abstract available.
Sensitization does not develop in utero.
Bønnelykke K, Pipper CB, Bisgaard H. Bønnelykke K, et al. J Allergy Clin Immunol. 2008 Mar;121(3):646-51. doi: 10.1016/j.jaci.2007.12.1149. J Allergy Clin Immunol. 2008. PMID: 18328892
Variants of DENND1B associated with asthma in children.
Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Sleiman PM, et al. Among authors: bonnelykke k. N Engl J Med. 2010 Jan 7;362(1):36-44. doi: 10.1056/NEJMoa0901867. Epub 2009 Dec 23. N Engl J Med. 2010. PMID: 20032318 Free article.
Long-term studies of the natural history of asthma in childhood.
Bisgaard H, Bønnelykke K. Bisgaard H, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2010 Aug;126(2):187-97; quiz 198-9. doi: 10.1016/j.jaci.2010.07.011. J Allergy Clin Immunol. 2010. PMID: 20688204 Review.
291 results