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Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.
Becker K, Cao S, Nilsson A, Erlandsson M, Hotop SK, Kuka J, Hansen J, Haldimann K, Grinberga S, Berruga-Fernández T, Huseby DL, Shariatgorji R, Lindmark E, Platzack B, Böttger EC, Crich D, Friberg LE, Vingsbo Lundberg C, Hughes D, Brönstrup M, Andrén PE, Liepinsh E, Hobbie SN. Becker K, et al. Among authors: bottger ec. EBioMedicine. 2021 Nov;73:103652. doi: 10.1016/j.ebiom.2021.103652. Epub 2021 Nov 2. EBioMedicine. 2021. PMID: 34740109 Free PMC article.
Mitochondrial deafness alleles confer misreading of the genetic code.
Hobbie SN, Bruell CM, Akshay S, Kalapala SK, Shcherbakov D, Böttger EC. Hobbie SN, et al. Among authors: bottger ec. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3244-9. doi: 10.1073/pnas.0707265105. Epub 2008 Feb 28. Proc Natl Acad Sci U S A. 2008. PMID: 18308926 Free PMC article.
315 results