Böhnert V - Search Results

1

Extracellular cGAMP is a cancer cell-produced immunotransmitter involved in radiation-induced anti-cancer immunity.

Carozza JA, Böhnert V, Nguyen KC, Skariah G, Shaw KE, Brown JA, Rafat M, von Eyben R, Graves EE, Glenn JS, Smith M, Li L. Carozza JA, et al. Among authors: bohnert v. Nat Cancer. 2020 Feb;1(2):184-196. doi: 10.1038/s43018-020-0028-4. Epub 2020 Feb 24. Nat Cancer. 2020. PMID: 33768207 Free PMC article.

2

Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP.

Carozza JA, Brown JA, Böhnert V, Fernandez D, AlSaif Y, Mardjuki RE, Smith M, Li L. Carozza JA, et al. Among authors: bohnert v. Cell Chem Biol. 2020 Nov 19;27(11):1347-1358.e5. doi: 10.1016/j.chembiol.2020.07.007. Epub 2020 Jul 28. Cell Chem Biol. 2020. PMID: 32726585 Free PMC article.

3

ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.

Carozza JA, Cordova AF, Brown JA, AlSaif Y, Böhnert V, Cao X, Mardjuki RE, Skariah G, Fernandez D, Li L. Carozza JA, et al. Among authors: bohnert v. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2119189119. doi: 10.1073/pnas.2119189119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588451 Free PMC article.

4

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

Lahey LJ, Mardjuki RE, Wen X, Hess GT, Ritchie C, Carozza JA, Böhnert V, Maduke M, Bassik MC, Li L. Lahey LJ, et al. Among authors: bohnert v. Mol Cell. 2020 Nov 19;80(4):578-591.e5. doi: 10.1016/j.molcel.2020.10.021. Epub 2020 Nov 9. Mol Cell. 2020. PMID: 33171122 Free article.

5

Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes.

Cordova AF, Ritchie C, Böhnert V, Li L. Cordova AF, et al. Among authors: bohnert v. ACS Cent Sci. 2021 Jun 23;7(6):1073-1088. doi: 10.1021/acscentsci.1c00440. Epub 2021 Jun 7. ACS Cent Sci. 2021. PMID: 34235268 Free PMC article.

6

IFN-Independent STING Signaling: Friend or Foe?

Böhnert V, Ritchie C, Li L. Böhnert V, et al. Immunity. 2020 Jul 14;53(1):8-10. doi: 10.1016/j.immuni.2020.06.021. Immunity. 2020. PMID: 32668231 Free article.

7

Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells.

Kübler K, Gehrke N, Riemann S, Böhnert V, Zillinger T, Hartmann E, Pölcher M, Rudlowski C, Kuhn W, Hartmann G, Barchet W. Kübler K, et al. Among authors: bohnert v. Cancer Res. 2010 Jul 1;70(13):5293-304. doi: 10.1158/0008-5472.CAN-10-0825. Epub 2010 Jun 15. Cancer Res. 2010. PMID: 20551064

8

Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.

Burgdorf S, Kautz A, Böhnert V, Knolle PA, Kurts C. Burgdorf S, et al. Among authors: bohnert v. Science. 2007 Apr 27;316(5824):612-6. doi: 10.1126/science.1137971. Science. 2007. PMID: 17463291

9

Improved transplantation outcome by epigenetic changes.

Schildberg FA, Hagmann CA, Böhnert V, Tolba RH. Schildberg FA, et al. Among authors: bohnert v. Transpl Immunol. 2010 Jul;23(3):104-10. doi: 10.1016/j.trim.2010.05.001. Epub 2010 May 13. Transpl Immunol. 2010. PMID: 20471480 Review.

10

A Model to Simulate Clinically Relevant Hypoxia in Humans.

Eichhorn L, Kessler F, Böhnert V, Erdfelder F, Reckendorf A, Meyer R, Ellerkmann RK. Eichhorn L, et al. Among authors: bohnert v. J Vis Exp. 2016 Dec 22;(118):54933. doi: 10.3791/54933. J Vis Exp. 2016. PMID: 28060323 Free PMC article.

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