Bérubé G - Search Results

1

Recent Advances in the Use of the Dimerization Strategy as a Means to Increase the Biological Potential of Natural or Synthetic Molecules.

Paquin A, Reyes-Moreno C, Bérubé G. Paquin A, et al. Among authors: berube g. Molecules. 2021 Apr 17;26(8):2340. doi: 10.3390/molecules26082340. Molecules. 2021. PMID: 33920597 Free PMC article. Review.

2

Natural and synthetic biologically active dimeric molecules: anticancer agents, anti-HIV agents, steroid derivatives and opioid antagonists.

Bérubé G. Bérubé G. Curr Med Chem. 2006;13(2):131-54. doi: 10.2174/092986706775197908. Curr Med Chem. 2006. PMID: 16472210 Review.

3

Advances in the development of hybrid anticancer drugs.

Fortin S, Bérubé G. Fortin S, et al. Among authors: berube g. Expert Opin Drug Discov. 2013 Aug;8(8):1029-47. doi: 10.1517/17460441.2013.798296. Epub 2013 May 7. Expert Opin Drug Discov. 2013. PMID: 23646979 Review.

4

New testosterone derivatives as semi-synthetic anticancer agents against prostate cancer: synthesis and preliminary biological evaluation.

Morin N, Bruneau J, Fortin S, Brasseur K, Leblanc V, Asselin E, Berube G. Morin N, et al. Among authors: berube g. Med Chem. 2015;11(6):531-9. doi: 10.2174/1573406411666150212120628. Med Chem. 2015. PMID: 25675439

5

Identification of an anti-inflammatory derivative with anti-cancer potential: The impact of each of its structural components on inflammatory responses in macrophages and bladder cancer cells.

Hamelin-Morrissette J, Cloutier S, Girouard J, Belgorosky D, Eiján AM, Legault J, Reyes-Moreno C, Bérubé G. Hamelin-Morrissette J, et al. Among authors: berube g. Eur J Med Chem. 2015;96:259-68. doi: 10.1016/j.ejmech.2015.04.026. Epub 2015 Apr 13. Eur J Med Chem. 2015. PMID: 25890076

6

Molecular therapy with derivatives of amino benzoic acid inhibits tumor growth and metastasis in murine models of bladder cancer through inhibition of TNFα/NFΚB and iNOS/NO pathways.

Girouard J, Belgorosky D, Hamelin-Morrissette J, Boulanger V, D'Orio E, Ramla D, Perron R, Charpentier L, Van Themsche C, Eiján AM, Bérubé G, Reyes-Moreno C. Girouard J, et al. Among authors: berube g. Biochem Pharmacol. 2020 Jun;176:113778. doi: 10.1016/j.bcp.2019.113778. Epub 2019 Dec 24. Biochem Pharmacol. 2020. PMID: 31877271

7

Biomolecular study and conjugation of two para-aminobenzoic acid derivatives with serum proteins: drug binding efficacy and protein structural analysis.

Chanphai P, Cloutier F, Oufqir Y, Leclerc MF, Eiján AM, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2021 Jan;39(1):79-90. doi: 10.1080/07391102.2020.1719889. Epub 2020 Feb 3. J Biomol Struct Dyn. 2021. PMID: 31980010

8

Binding efficacy of aminobenzoic acid derivatives with DNA duplex: drug binding sites and DNA structure and dynamics.

Chanphai P, Cloutier F, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2021 Apr;39(6):2278-2283. doi: 10.1080/07391102.2020.1740792. Epub 2020 Mar 24. J Biomol Struct Dyn. 2021. PMID: 32151202

9

Locating the binding sites of two aminobenzoic acid derivatives on tRNA: drug binding efficacy and RNA structure.

Chanphai P, Cloutier F, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2022 Jan;40(1):130-135. doi: 10.1080/07391102.2020.1808076. Epub 2020 Aug 18. J Biomol Struct Dyn. 2022. PMID: 32811341

10

Innovative C₂-symmetric testosterone and androstenedione dimers: Design, synthesis, biological evaluation on prostate cancer cell lines and binding study to recombinant CYP3A4.

Paquin A, Oufqir Y, Sevrioukova IF, Reyes-Moreno C, Bérubé G. Paquin A, et al. Among authors: berube g. Eur J Med Chem. 2021 Aug 5;220:113496. doi: 10.1016/j.ejmech.2021.113496. Epub 2021 Apr 24. Eur J Med Chem. 2021. PMID: 33933755 Free PMC article.

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