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Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade.
Sci Transl Med. 2022 Nov 2;14(669):eabj1270. doi: 10.1126/scitranslmed.abj1270. Epub 2022 Nov 2.
Sci Transl Med. 2022.
PMID: 36322632
Free PMC article.
The sialoglycan-Siglec glyco-immune checkpoint - a target for improving innate and adaptive anti-cancer immunity.
Bärenwaldt A, Läubli H.
Bärenwaldt A, et al.
Expert Opin Ther Targets. 2019 Oct;23(10):839-853. doi: 10.1080/14728222.2019.1667977. Epub 2019 Sep 23.
Expert Opin Ther Targets. 2019.
PMID: 31524529
Review.
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Targeting immunoliposomes to EGFR-positive glioblastoma.
Kasenda B, König D, Manni M, Ritschard R, Duthaler U, Bartoszek E, Bärenwaldt A, Deuster S, Hutter G, Cordier D, Mariani L, Hench J, Frank S, Krähenbühl S, Zippelius A, Rochlitz C, Mamot C, Wicki A, Läubli H.
Kasenda B, et al. Among authors: barenwaldt a.
ESMO Open. 2022 Feb;7(1):100365. doi: 10.1016/j.esmoop.2021.100365. Epub 2022 Jan 5.
ESMO Open. 2022.
PMID: 34998092
Free PMC article.
Clinical Trial.
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Siglec Receptors Modulate Dendritic Cell Activation and Antigen Presentation to T Cells in Cancer.
Wang J, Manni M, Bärenwaldt A, Wieboldt R, Kirchhammer N, Ivanek R, Stanczak M, Zippelius A, König D, Rodrigues Manutano N, Läubli H.
Wang J, et al. Among authors: barenwaldt a.
Front Cell Dev Biol. 2022 Mar 3;10:828916. doi: 10.3389/fcell.2022.828916. eCollection 2022.
Front Cell Dev Biol. 2022.
PMID: 35309936
Free PMC article.
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Changes of peripheral T cell subsets in melanoma patients with immune-related adverse events.
Müller B, Bärenwaldt A, Herzig P, Zippelius A, Maul LV, Hess V, König D, Läubli H.
Müller B, et al. Among authors: barenwaldt a.
Front Immunol. 2023 Apr 12;14:1125111. doi: 10.3389/fimmu.2023.1125111. eCollection 2023.
Front Immunol. 2023.
PMID: 37122748
Free PMC article.
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Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation.
Conti G, Bärenwaldt A, Rabbani S, Mühlethaler T, Sarcevic M, Jiang X, Schwardt O, Ricklin D, Pieters RJ, Läubli H, Ernst B.
Conti G, et al. Among authors: barenwaldt a.
Angew Chem Int Ed Engl. 2023 Dec 21;62(52):e202314280. doi: 10.1002/anie.202314280. Epub 2023 Nov 23.
Angew Chem Int Ed Engl. 2023.
PMID: 37947772
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NKp46 Calibrates Tumoricidal Potential of Type 1 Innate Lymphocytes by Regulating TRAIL Expression.
Turchinovich G, Ganter S, Bärenwaldt A, Finke D.
Turchinovich G, et al. Among authors: barenwaldt a.
J Immunol. 2018 Jun 1;200(11):3762-3768. doi: 10.4049/jimmunol.1701333. Epub 2018 Apr 16.
J Immunol. 2018.
PMID: 29661825
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Humic material induces behavioral and global transcriptional responses in the nematode Caenorhabditis elegans.
Menzel R, Stürzenbaum S, Bärenwaldt A, Kulas J, Steinberg CE.
Menzel R, et al. Among authors: barenwaldt a.
Environ Sci Technol. 2005 Nov 1;39(21):8324-32. doi: 10.1021/es050884s.
Environ Sci Technol. 2005.
PMID: 16294870
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