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Neuraminidase is a host-directed approach to regulate neutrophil responses in sepsis and COVID-19.
de Oliveira Formiga R, Amaral FC, Souza CF, Mendes DAGB, Wanderley CWS, Lorenzini CB, Santos AA, Antônia J, Faria LF, Natale CC, Paula NM, Silva PCS, Fonseca FR, Aires L, Heck N, Starick MR, Queiroz-Junior CM, Santos FRS, de Souza FRO, Costa VV, Barroso SPC, Morrot A, Van Weyenbergh J, Sordi R, Alisson-Silva F, Cunha FQ, Rocha EL, Chollet-Martin S, Hurtado-Nedelec MM, Martin C, Burgel PR, Mansur DS, Maurici R, Macauley MS, Báfica A, Witko-Sarsat V, Spiller F. de Oliveira Formiga R, et al. Among authors: bafica a. Br J Pharmacol. 2023 Jun;180(11):1460-1481. doi: 10.1111/bph.16013. Epub 2023 Jan 13. Br J Pharmacol. 2023. PMID: 36526272 Free PMC article.
Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge.
Mambelli F, Marinho FV, Andrade JM, de Araujo ACVSC, Abuna RPF, Fabri VMR, Santos BPO, da Silva JS, de Magalhães MTQ, Homan EJ, Leite LCC, Dias GBM, Heck N, Mendes DAGB, Mansur DS, Báfica A, Oliveira SC. Mambelli F, et al. Among authors: bafica a. J Immunol. 2023 Jun 15;210(12):1925-1937. doi: 10.4049/jimmunol.2200731. J Immunol. 2023. PMID: 37098890
ISG15/USP18/STAT2 is a molecular hub regulating IFN I-mediated control of Dengue and Zika virus replication.
Espada CE, da Rocha EL, Ricciardi-Jorge T, Dos Santos AA, Soares ZG, Malaquias G, Patrício DO, Gonzalez Kozlova E, Dos Santos PF, Bordignon J, Sanford TJ, Fajardo T, Sweeney TR, Báfica A, Mansur DS. Espada CE, et al. Among authors: bafica a. Front Immunol. 2024 Feb 7;15:1331731. doi: 10.3389/fimmu.2024.1331731. eCollection 2024. Front Immunol. 2024. PMID: 38384473 Free PMC article.
The Endogenous Retinoic Acid Receptor Pathway Is Exploited by Mycobacterium tuberculosis during Infection, Both In Vitro and In Vivo.
Tenório de Menezes YK, Eto C, de Oliveira J, Larson EC, Mendes DAGB, Dias GBM, Delgobo M, Gubernat AK, Gleim JL, Munari EL, Starick M, Ferreira F, Mansur DS, Costa DL, Scanga CA, Báfica A. Tenório de Menezes YK, et al. Among authors: bafica a. J Immunol. 2023 Aug 15;211(4):601-611. doi: 10.4049/jimmunol.2200555. J Immunol. 2023. PMID: 37395686
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
Gonçalves RM, Delgobo M, Agnes JP, das Neves RN, Falchetti M, Casagrande T, Garcia APV, Vieira TC, Somensi N, Bruxel MA, Mendes DAGB, Rafacho A, Báfica A, Gelain DP, Moreira JCF, Cassali GD, Bishop AJR, Zanotto-Filho A. Gonçalves RM, et al. Among authors: bafica a. Cancer Lett. 2021 Apr 1;502:44-57. doi: 10.1016/j.canlet.2021.01.003. Epub 2021 Jan 9. Cancer Lett. 2021. PMID: 33429006 Free article.
Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19.
de Oliveira Formiga R, Amaral FC, Souza CF, Mendes DAGB, Wanderley CWS, Lorenzini CB, Santos AA, Antônia J, Faria LF, Natale CC, Paula NM, Silva PCS, Fonseca FR, Aires L, Heck N, Starick MR, Queiroz-Junior CM, Santos FRS, de Souza FRO, Costa VV, Barroso SPC, Morrot A, Van Weyenbergh J, Sordi R, Alisson-Silva F, Cunha FQ, Rocha EL, Chollet-Martin S, Hurtado-Nedelec MM, Martin C, Burgel PR, Mansur DS, Maurici R, Macauley MS, Báfica A, Witko-Sarsat V, Spiller F. de Oliveira Formiga R, et al. Among authors: bafica a. bioRxiv [Preprint]. 2022 Oct 14:2020.11.12.379115. doi: 10.1101/2020.11.12.379115. bioRxiv. 2022. PMID: 33200130 Free PMC article. Preprint.
IL-21 treatment recovers follicular helper T cells and neutralizing antibody production in respiratory syncytial virus infection.
Gassen RB, Fazolo T, Nascimento de Freitas D, Borges TJ, Lima K, Antunes GL, Maito F, Bueno Mendes DA, Báfica A, Rodrigues LC Jr, Stein R, Duarte de Souza AP, Bonorino C. Gassen RB, et al. Among authors: bafica a. Immunol Cell Biol. 2021 Mar;99(3):309-322. doi: 10.1111/imcb.12418. Epub 2020 Dec 4. Immunol Cell Biol. 2021. PMID: 33068449
70 results