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Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions.
Grajales-Reyes GE, Báez-Pagán CA, Zhu H, Grajales-Reyes JG, Delgado-Vélez M, García-Beltrán WF, Luciano CA, Quesada O, Ramírez R, Gómez CM, Lasalde-Dominicci JA. Grajales-Reyes GE, et al. Pharmacogenomics J. 2013 Aug;13(4):362-8. doi: 10.1038/tpj.2012.21. Epub 2012 Jun 12. Pharmacogenomics J. 2013. PMID: 22688219 Free PMC article.
Potential role of caveolin-1-positive domains in the regulation of the acetylcholine receptor's activatable pool: implications in the pathogenesis of a novel congenital myasthenic syndrome.
Báez-Pagán CA, Martínez-Ortiz Y, Otero-Cruz JD, Salgado-Villanueva IK, Velázquez G, Ortiz-Acevedo A, Quesada O, Silva WI, Lasalde-Dominicci JA. Báez-Pagán CA, et al. Channels (Austin). 2008 May-Jun;2(3):180-90. doi: 10.4161/chan.2.3.6155. Epub 2008 May 18. Channels (Austin). 2008. PMID: 18836288 Free PMC article.
Effects of lipid-analog detergent solubilization on the functionality and lipidic cubic phase mobility of the Torpedo californica nicotinic acetylcholine receptor.
Padilla-Morales LF, Morales-Pérez CL, De La Cruz-Rivera PC, Asmar-Rovira G, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Padilla-Morales LF, et al. J Membr Biol. 2011 Oct;243(1-3):47-58. doi: 10.1007/s00232-011-9392-4. Epub 2011 Sep 16. J Membr Biol. 2011. PMID: 21922299 Free PMC article.
Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome.
Zhu H, Grajales-Reyes GE, Alicea-Vázquez V, Grajales-Reyes JG, Robinson K, Pytel P, Báez-Pagán CA, Lasalde-Dominicci JA, Gomez CM. Zhu H, et al. Among authors: baez pagan ca. Exp Neurol. 2015 Aug;270:88-94. doi: 10.1016/j.expneurol.2014.10.008. Epub 2014 Oct 23. Exp Neurol. 2015. PMID: 25448156 Free PMC article.
Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit.
Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA. Biaggi-Labiosa NM, et al. Among authors: baez pagan ca. Neuropharmacology. 2015 Dec;99:273-84. doi: 10.1016/j.neuropharm.2015.04.022. Epub 2015 May 6. Neuropharmacology. 2015. PMID: 25957813 Free PMC article.
Lateral diffusion, function, and expression of the slow channel congenital myasthenia syndrome αC418W nicotinic receptor mutation with changes in lipid raft components.
Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Baéz-Pagán CA, Martínez HL, Vélez-Arroyo KP, Quesada O, Lasalde-Dominicci JA. Oyola-Cintrón J, et al. Among authors: baez pagan ca. J Biol Chem. 2015 Oct 30;290(44):26790-800. doi: 10.1074/jbc.M115.678573. Epub 2015 Sep 9. J Biol Chem. 2015. PMID: 26354438 Free PMC article.
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