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Modeling and countering the effects of cosmic radiation using bioengineered human tissues.
Tavakol DN, Nash TR, Kim Y, He S, Fleischer S, Graney PL, Brown JA, Liberman M, Tamargo M, Harken A, Ferrando AA, Amundson S, Garty G, Azizi E, Leong KW, Brenner DJ, Vunjak-Novakovic G. Tavakol DN, et al. Among authors: azizi e. Biomaterials. 2023 Oct;301:122267. doi: 10.1016/j.biomaterials.2023.122267. Epub 2023 Aug 11. Biomaterials. 2023. PMID: 37633022
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.
He S, Jin Y, Nazaret A, Shi L, Chen X, Rampersaud S, Dhillon BS, Valdez I, Friend LE, Fan JL, Park CY, Mintz RL, Lao YH, Carrera D, Fang KW, Mehdi K, Rohde M, McFaline-Figueroa JL, Blei D, Leong KW, Rudensky AY, Plitas G, Azizi E. He S, et al. Among authors: azizi e. Nat Biotechnol. 2024 Mar 21. doi: 10.1038/s41587-024-02173-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 38514799
Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.
Wang Y, Fan JL, Melms JC, Amin AD, Georgis Y, Barrera I, Ho P, Tagore S, Abril-Rodríguez G, He S, Jin Y, Biermann J, Hofree M, Caprio L, Berhe S, Khan SA, Henick BS, Ribas A, Macosko EZ, Chen F, Taylor AM, Schwartz GK, Carvajal RD, Azizi E, Izar B. Wang Y, et al. Among authors: azizi e. Nat Genet. 2023 Jan;55(1):19-25. doi: 10.1038/s41588-022-01268-9. Epub 2023 Jan 9. Nat Genet. 2023. PMID: 36624340 Free PMC article.
Deep generative model deciphers derailed trajectories in acute myeloid leukemia.
Nazaret A, Fan JL, Lavallée VP, Cornish AE, Kiseliovas V, Masilionis I, Chun J, Bowman RL, Eisman SE, Wang J, Shi L, Levine RL, Mazutis L, Blei D, Pe'er D, Azizi E. Nazaret A, et al. Among authors: azizi e. bioRxiv [Preprint]. 2023 Nov 15:2023.11.11.566719. doi: 10.1101/2023.11.11.566719. bioRxiv. 2023. PMID: 38014231 Free PMC article. Preprint.
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.
Biermann J, Melms JC, Amin AD, Wang Y, Caprio LA, Karz A, Tagore S, Barrera I, Ibarra-Arellano MA, Andreatta M, Fullerton BT, Gretarsson KH, Sahu V, Mangipudy VS, Nguyen TTT, Nair A, Rogava M, Ho P, Koch PD, Banu M, Humala N, Mahajan A, Walsh ZH, Shah SB, Vaccaro DH, Caldwell B, Mu M, Wünnemann F, Chazotte M, Berhe S, Luoma AM, Driver J, Ingham M, Khan SA, Rapisuwon S, Slingluff CL Jr, Eigentler T, Röcken M, Carvajal R, Atkins MB, Davies MA, Agustinus A, Bakhoum SF, Azizi E, Siegelin M, Lu C, Carmona SJ, Hibshoosh H, Ribas A, Canoll P, Bruce JN, Bi WL, Agrawal P, Schapiro D, Hernando E, Macosko EZ, Chen F, Schwartz GK, Izar B. Biermann J, et al. Among authors: azizi e. Cell. 2022 Jul 7;185(14):2591-2608.e30. doi: 10.1016/j.cell.2022.06.007. Cell. 2022. PMID: 35803246 Free PMC article.
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy.
Bachireddy P, Azizi E, Burdziak C, Nguyen VN, Ennis CS, Maurer K, Park CY, Choo ZN, Li S, Gohil SH, Ruthen NG, Ge Z, Keskin DB, Cieri N, Livak KJ, Kim HT, Neuberg DS, Soiffer RJ, Ritz J, Alyea EP, Pe'er D, Wu CJ. Bachireddy P, et al. Among authors: azizi e. Cell Rep. 2021 Nov 9;37(6):109992. doi: 10.1016/j.celrep.2021.109992. Cell Rep. 2021. PMID: 34758319 Free PMC article.
A gene-environment-induced epigenetic program initiates tumorigenesis.
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan W, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe'er D, Lowe SW. Alonso-Curbelo D, et al. Among authors: azizi e. Nature. 2021 Feb;590(7847):642-648. doi: 10.1038/s41586-020-03147-x. Epub 2021 Feb 3. Nature. 2021. PMID: 33536616 Free PMC article.
325 results