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Rationale and design of the Kidney Precision Medicine Project.
de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J; Kidney Precision Medicine Project. de Boer IH, et al. Among authors: azeloglu eu. Kidney Int. 2021 Mar;99(3):498-510. doi: 10.1016/j.kint.2020.08.039. Kidney Int. 2021. PMID: 33637194 Free PMC article.
Interconnected network motifs control podocyte morphology and kidney function.
Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R. Azeloglu EU, et al. Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621. Sci Signal. 2014. PMID: 24497609 Free PMC article.
Kidney tissue engineering for precision medicine.
Anandakrishnan N, Azeloglu EU. Anandakrishnan N, et al. Among authors: azeloglu eu. Nat Rev Nephrol. 2020 Nov;16(11):623-624. doi: 10.1038/s41581-020-00355-6. Nat Rev Nephrol. 2020. PMID: 32934358 Review. No abstract available.
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, Parikh S, Zhang G, Dobi D, Dunn KW, Otto EA, Anderton CR, Carson JM, Luo J, Park C, Hamidi H, Zhou J, Hoover P, Schroeder A, Joanes M, Azeloglu EU, Sealfon R, Winfree S, Steck B, He Y, D'Agati V, Iyengar R, Troyanskaya OG, Barisoni L, Gaut J, Zhang K, Laszik Z, Rovin BH, Dagher PC, Sharma K, Sarwal MM, Hodgin JB, Alpers CE, Kretzler M, Jain S. El-Achkar TM, et al. Among authors: azeloglu eu. Physiol Genomics. 2021 Jan 1;53(1):1-11. doi: 10.1152/physiolgenomics.00104.2020. Epub 2020 Nov 16. Physiol Genomics. 2021. PMID: 33197228 Free PMC article.
Protein structure-based gene expression signatures.
Rahman R, Zatorski N, Hansen J, Xiong Y, van Hasselt JGC, Sobie EA, Birtwistle MR, Azeloglu EU, Iyengar R, Schlessinger A. Rahman R, et al. Among authors: azeloglu eu. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2014866118. doi: 10.1073/pnas.2014866118. Proc Natl Acad Sci U S A. 2021. PMID: 33941686 Free PMC article.
Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis.
Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS; Kidney Precision Medicine Project (KPMP). Schmidt IM, et al. Kidney Int. 2021 Sep;100(3):672-683. doi: 10.1016/j.kint.2021.04.037. Epub 2021 May 27. Kidney Int. 2021. PMID: 34051265 Free PMC article.
A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project.
Butler CR, Appelbaum PS, Ascani H, Aulisio M, Campbell CE, de Boer IH, Dighe AL, Hall DE, Himmelfarb J, Knight R, Mehl K, Murugan R, Rosas SE, Sedor JR, O'Toole JF, Tuttle KR, Waikar SS, Freeman M; Kidney Precision Medicine Project. Butler CR, et al. Am J Kidney Dis. 2022 Jul;80(1):132-138. doi: 10.1053/j.ajkd.2021.10.006. Epub 2021 Dec 4. Am J Kidney Dis. 2022. PMID: 34871700 Free PMC article.
78 results