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102 results

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Page 1
Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma.
Federico C, Alhallak K, Sun J, Duncan K, Azab F, Sudlow GP, de la Puente P, Muz B, Kapoor V, Zhang L, Yuan F, Markovic M, Kotsybar J, Wasden K, Guenthner N, Gurley S, King J, Kohnen D, Salama NN, Thotala D, Hallahan DE, Vij R, DiPersio JF, Achilefu S, Azab AK. Federico C, et al. Among authors: azab f, azab ak. Nat Commun. 2020 Nov 27;11(1):6037. doi: 10.1038/s41467-020-19932-1. Nat Commun. 2020. PMID: 33247158 Free PMC article.
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson AL, Alt C, Burwick N, Roccaro AM, Ngo HT, Farag M, Melhem MR, Sacco A, Munshi NC, Hideshima T, Rollins BJ, Anderson KC, Kung AL, Lin CP, Ghobrial IM. Azab AK, et al. Among authors: azab f. Blood. 2009 Apr 30;113(18):4341-51. doi: 10.1182/blood-2008-10-186668. Epub 2009 Jan 12. Blood. 2009. PMID: 19139079 Free PMC article.
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM. Roccaro AM, et al. Among authors: azab f, azab ak. Blood. 2009 Jun 25;113(26):6669-80. doi: 10.1182/blood-2009-01-198408. Epub 2009 Apr 28. Blood. 2009. PMID: 19401561 Free PMC article.
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM. Azab AK, et al. Among authors: azab f. Blood. 2009 Jul 16;114(3):619-29. doi: 10.1182/blood-2009-01-199281. Epub 2009 May 14. Blood. 2009. PMID: 19443661 Free PMC article.
Src tyrosine kinase regulates adhesion and chemotaxis in Waldenstrom macroglobulinemia.
Ngo HT, Azab AK, Farag M, Jia X, Melhem MM, Runnels J, Roccaro AM, Azab F, Sacco A, Leleu X, Anderson KC, Ghobrial IM. Ngo HT, et al. Among authors: azab f, azab ak. Clin Cancer Res. 2009 Oct 1;15(19):6035-41. doi: 10.1158/1078-0432.CCR-09-0718. Epub 2009 Sep 15. Clin Cancer Res. 2009. PMID: 19755386 Free PMC article.
Carfilzomib-dependent selective inhibition of the chymotrypsin-like activity of the proteasome leads to antitumor activity in Waldenstrom's Macroglobulinemia.
Sacco A, Aujay M, Morgan B, Azab AK, Maiso P, Liu Y, Zhang Y, Azab F, Ngo HT, Issa GC, Quang P, Roccaro AM, Ghobrial IM. Sacco A, et al. Among authors: azab f, azab ak. Clin Cancer Res. 2011 Apr 1;17(7):1753-64. doi: 10.1158/1078-0432.CCR-10-2130. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355079
Targeting the bone marrow in Waldenstrom macroglobulinemia.
Ghobrial IM, Zhang Y, Liu Y, Ngo H, Azab F, Sacco A, Azab A, Maiso P, Morgan B, Quang P, Issa GC, Leleu X, Roccaro AM. Ghobrial IM, et al. Clin Lymphoma Myeloma Leuk. 2011 Jun;11 Suppl 1(Suppl 1):S65-9. doi: 10.1016/j.clml.2011.03.022. Epub 2011 Apr 30. Clin Lymphoma Myeloma Leuk. 2011. PMID: 22035751 Free PMC article. Review.
Defining the role of TORC1/2 in multiple myeloma.
Maiso P, Liu Y, Morgan B, Azab AK, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro AM, Rommel C, Ghobrial IM. Maiso P, et al. Among authors: azab f, azab ak. Blood. 2011 Dec 22;118(26):6860-70. doi: 10.1182/blood-2011-03-342394. Epub 2011 Nov 1. Blood. 2011. PMID: 22045983 Free PMC article.
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.
Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM. Azab AK, et al. Among authors: azab f. Blood. 2012 Feb 9;119(6):1468-78. doi: 10.1182/blood-2011-07-368050. Epub 2011 Nov 16. Blood. 2012. PMID: 22096244 Free PMC article.
102 results