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Synthesis and potential antitumor activity of 7-(4-substituted piperazin-1-yl)-4-oxoquinolines based on ciprofloxacin and norfloxacin scaffolds: in silico studies.
Abdel-Aziz AA, El-Azab AS, Alanazi AM, Asiri YA, Al-Suwaidan IA, Maarouf AR, Ayyad RR, Shawer TZ. Abdel-Aziz AA, et al. Among authors: ayyad rr. J Enzyme Inhib Med Chem. 2016 Oct;31(5):796-809. doi: 10.3109/14756366.2015.1069288. Epub 2015 Jul 30. J Enzyme Inhib Med Chem. 2016. PMID: 26226179
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives.
Eldehna WM, Abou-Seri SM, El Kerdawy AM, Ayyad RR, Hamdy AM, Ghabbour HA, Ali MM, Abou El Ella DA. Eldehna WM, et al. Among authors: ayyad rr. Eur J Med Chem. 2016 May 4;113:50-62. doi: 10.1016/j.ejmech.2016.02.029. Epub 2016 Feb 15. Eur J Med Chem. 2016. PMID: 26922228
24 results