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Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.
Nat Struct Mol Biol. 2017 Feb;24(2):108-113. doi: 10.1038/nsmb.3329. Epub 2016 Dec 19.
Nat Struct Mol Biol. 2017.
PMID: 27991902
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors.
Bregman H, Simard JR, Andrews KL, Ayube S, Chen H, Gunaydin H, Guzman-Perez A, Hu J, Huang L, Huang X, Krolikowski PH, Lehto SG, Lewis RT, Michelsen K, Pegman P, Plant MH, Shaffer PL, Teffera Y, Yi S, Zhang M, Gingras J, DiMauro EF.
Bregman H, et al. Among authors: ayube s.
J Med Chem. 2017 Feb 9;60(3):1105-1125. doi: 10.1021/acs.jmedchem.6b01496. Epub 2016 Dec 21.
J Med Chem. 2017.
PMID: 28001399
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In-column dilution: Improving volume loadability in reverse phase gradient chromatography through the use of a silica pre-column.
Miller L, Ayube SJ.
Miller L, et al. Among authors: ayube sj.
J Chromatogr A. 2020 May 10;1618:460897. doi: 10.1016/j.chroma.2020.460897. Epub 2020 Jan 23.
J Chromatogr A. 2020.
PMID: 32007218
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