Ayres CM - Search Results

1

Structural dissimilarity from self drives neoepitope escape from immune tolerance.

Devlin JR, Alonso JA, Ayres CM, Keller GLJ, Bobisse S, Vander Kooi CW, Coukos G, Gfeller D, Harari A, Baker BM. Devlin JR, et al. Among authors: ayres cm. Nat Chem Biol. 2020 Nov;16(11):1269-1276. doi: 10.1038/s41589-020-0610-1. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807968 Free PMC article.

2

Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition.

Hawse WF, Gloor BE, Ayres CM, Kho K, Nuter E, Baker BM. Hawse WF, et al. Among authors: ayres cm. J Biol Chem. 2013 Aug 23;288(34):24372-81. doi: 10.1074/jbc.M113.490664. Epub 2013 Jul 8. J Biol Chem. 2013. PMID: 23836912 Free PMC article.

3

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity.

Duan F, Duitama J, Al Seesi S, Ayres CM, Corcelli SA, Pawashe AP, Blanchard T, McMahon D, Sidney J, Sette A, Baker BM, Mandoiu II, Srivastava PK. Duan F, et al. Among authors: ayres cm. J Exp Med. 2014 Oct 20;211(11):2231-48. doi: 10.1084/jem.20141308. Epub 2014 Sep 22. J Exp Med. 2014. PMID: 25245761 Free PMC article.

4

Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity.

Ayres CM, Scott DR, Corcelli SA, Baker BM. Ayres CM, et al. Sci Rep. 2016 Apr 27;6:25070. doi: 10.1038/srep25070. Sci Rep. 2016. PMID: 27118724 Free PMC article.

5

A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces.

Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, Baker BM. Riley TP, et al. Among authors: ayres cm. Protein Eng Des Sel. 2016 Dec;29(12):595-606. doi: 10.1093/protein/gzw050. Epub 2016 Sep 13. Protein Eng Des Sel. 2016. PMID: 27624308 Free PMC article.

6

Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition.

Ayres CM, Riley TP, Corcelli SA, Baker BM. Ayres CM, et al. J Chem Inf Model. 2017 Aug 28;57(8):1990-1998. doi: 10.1021/acs.jcim.7b00118. Epub 2017 Jul 25. J Chem Inf Model. 2017. PMID: 28696685 Free PMC article.

7

Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings.

Ayres CM, Corcelli SA, Baker BM. Ayres CM, et al. Front Immunol. 2017 Aug 7;8:935. doi: 10.3389/fimmu.2017.00935. eCollection 2017. Front Immunol. 2017. PMID: 28824655 Free PMC article. Review.

8

Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.

Hellman LM, Foley KC, Singh NK, Alonso JA, Riley TP, Devlin JR, Ayres CM, Keller GLJ, Zhang Y, Vander Kooi CW, Nishimura MI, Baker BM. Hellman LM, et al. Among authors: ayres cm. Mol Ther. 2019 Feb 6;27(2):300-313. doi: 10.1016/j.ymthe.2018.12.010. Epub 2018 Dec 14. Mol Ther. 2019. PMID: 30617019 Free PMC article.

9

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility.

Ayres CM, Abualrous ET, Bailey A, Abraham C, Hellman LM, Corcelli SA, Noé F, Elliott T, Baker BM. Ayres CM, et al. Front Immunol. 2019 May 3;10:966. doi: 10.3389/fimmu.2019.00966. eCollection 2019. Front Immunol. 2019. PMID: 31130956 Free PMC article.

10

Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen.

Singh NK, Abualrous ET, Ayres CM, Noé F, Gowthaman R, Pierce BG, Baker BM. Singh NK, et al. Among authors: ayres cm. Proteins. 2020 Mar;88(3):503-513. doi: 10.1002/prot.25829. Epub 2019 Oct 21. Proteins. 2020. PMID: 31589793 Free PMC article.

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