Aylon Y - Search Results

1

TAZ facilitates breast tumor growth by promoting an immune-suppressive tumor microenvironment.

Gershoni A, Hassin O, Nataraj NB, Baruch S, Avioz-Seligman A, Pirona AC, Fellus-Alyagor L, Meir Salame T, Mukherjee S, Mallel G, Yarden Y, Aylon Y, Oren M. Gershoni A, et al. Among authors: aylon y. Mol Oncol. 2023 Dec;17(12):2675-2693. doi: 10.1002/1878-0261.13525. Epub 2023 Oct 16. Mol Oncol. 2023. PMID: 37716913 Free PMC article.

2

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization.

Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M. Aylon Y, et al. Genes Dev. 2006 Oct 1;20(19):2687-700. doi: 10.1101/gad.1447006. Genes Dev. 2006. PMID: 17015431 Free PMC article.

3

Living with p53, dying of p53.

Aylon Y, Oren M. Aylon Y, et al. Cell. 2007 Aug 24;130(4):597-600. doi: 10.1016/j.cell.2007.08.005. Cell. 2007. PMID: 17719538 Free article. Review.

4

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M. Shema E, et al. Among authors: aylon y. Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008. Genes Dev. 2008. PMID: 18832071 Free PMC article.

5

Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.

Aylon Y, Yabuta N, Besserglick H, Buganim Y, Rotter V, Nojima H, Oren M. Aylon Y, et al. Oncogene. 2009 Dec 17;28(50):4469-79. doi: 10.1038/onc.2009.270. Epub 2009 Oct 26. Oncogene. 2009. PMID: 19855428 Free PMC article.

6

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1.

Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, Lu X, Oren M. Aylon Y, et al. Genes Dev. 2010 Nov 1;24(21):2420-9. doi: 10.1101/gad.1954410. Genes Dev. 2010. PMID: 21041410 Free PMC article.

7

New plays in the p53 theater.

Aylon Y, Oren M. Aylon Y, et al. Curr Opin Genet Dev. 2011 Feb;21(1):86-92. doi: 10.1016/j.gde.2010.10.002. Epub 2010 Nov 4. Curr Opin Genet Dev. 2011. PMID: 21317061 Free PMC article. Review.

8

p53: guardian of ploidy.

Aylon Y, Oren M. Aylon Y, et al. Mol Oncol. 2011 Aug;5(4):315-23. doi: 10.1016/j.molonc.2011.07.007. Epub 2011 Jul 30. Mol Oncol. 2011. PMID: 21852209 Free PMC article. Review.

9

Lats2 is critical for the pluripotency and proper differentiation of stem cells.

Aylon Y, Sarver A, Tovy A, Ainbinder E, Oren M. Aylon Y, et al. Cell Death Differ. 2014 Apr;21(4):624-33. doi: 10.1038/cdd.2013.188. Epub 2014 Jan 10. Cell Death Differ. 2014. PMID: 24413153 Free PMC article.

10

Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth.

Adi Harel S, Bossel Ben-Moshe N, Aylon Y, Bublik DR, Moskovits N, Toperoff G, Azaiza D, Biagoni F, Fuchs G, Wilder S, Hellman A, Blandino G, Domany E, Oren M. Adi Harel S, et al. Among authors: aylon y. Cell Death Differ. 2015 Aug;22(8):1328-40. doi: 10.1038/cdd.2014.221. Epub 2015 Jan 16. Cell Death Differ. 2015. PMID: 25591738 Free PMC article.

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