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New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Filimonov AS, Chepanova AA, Luzina OA, Zakharenko AL, Zakharova OD, Ilina ES, Dyrkheeva NS, Kuprushkin MS, Kolotaev AV, Khachatryan DS, Patel J, Leung IKH, Chand R, Ayine-Tora DM, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Filimonov AS, et al. Among authors: ayine tora dm. Molecules. 2019 Oct 15;24(20):3711. doi: 10.3390/molecules24203711. Molecules. 2019. PMID: 31619021 Free PMC article.
Virtual screening and biophysical studies lead to HSP90 inhibitors.
Huang R, Ayine-Tora DM, Muhammad Rosdi MN, Li Y, Reynisson J, Leung IKH. Huang R, et al. Among authors: ayine tora dm. Bioorg Med Chem Lett. 2017 Jan 15;27(2):277-281. doi: 10.1016/j.bmcl.2016.11.059. Epub 2016 Nov 23. Bioorg Med Chem Lett. 2017. PMID: 27913182
Anti-influenza activity of diazaadamantanes combined with monoterpene moieties.
Suslov E, Zarubaev VV, Slita AV, Ponomarev K, Korchagina D, Ayine-Tora DM, Reynisson J, Volcho K, Salakhutdinov N. Suslov E, et al. Among authors: ayine tora dm. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4531-4535. doi: 10.1016/j.bmcl.2017.08.062. Epub 2017 Sep 1. Bioorg Med Chem Lett. 2017. PMID: 28886889
From Catalysis to Cancer: Toward Structure-Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents.
Lam NYS, Truong D, Burmeister H, Babak MV, Holtkamp HU, Movassaghi S, Ayine-Tora DM, Zafar A, Kubanik M, Oehninger L, Söhnel T, Reynisson J, Jamieson SMF, Gaiddon C, Ott I, Hartinger CG. Lam NYS, et al. Among authors: ayine tora dm. Inorg Chem. 2018 Nov 19;57(22):14427-14434. doi: 10.1021/acs.inorgchem.8b02634. Epub 2018 Nov 8. Inorg Chem. 2018. PMID: 30406647
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Khomenko TM, Zakharenko AL, Chepanova AA, Ilina ES, Zakharova OD, Kaledin VI, Nikolin VP, Popova NA, Korchagina DV, Reynisson J, Chand R, Ayine-Tora DM, Patel J, Leung IKH, Volcho KP, Salakhutdinov NF, Lavrik OI. Khomenko TM, et al. Among authors: ayine tora dm. Int J Mol Sci. 2019 Dec 23;21(1):126. doi: 10.3390/ijms21010126. Int J Mol Sci. 2019. PMID: 31878088 Free PMC article.
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
Il'ina IV, Dyrkheeva NS, Zakharenko AL, Sidorenko AY, Li-Zhulanov NS, Korchagina DV, Chand R, Ayine-Tora DM, Chepanova AA, Zakharova OD, Ilina ES, Reynisson J, Malakhova AA, Medvedev SP, Zakian SM, Volcho KP, Salakhutdinov NF, Lavrik OI. Il'ina IV, et al. Among authors: ayine tora dm. Molecules. 2020 Jul 31;25(15):3496. doi: 10.3390/molecules25153496. Molecules. 2020. PMID: 32751997 Free PMC article.
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