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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Guièze R, Liu VM, Rosebrock D, Jourdain AA, Hernández-Sánchez M, Martinez Zurita A, Sun J, Ten Hacken E, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygün O, Iorgulescu JB, Zhang W, Notarangelo G, Livitz D, Li S, Davids MS, Biran A, Fernandes SM, Brown JR, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ, Letai AG, Neuberg D, Harper JW, Carr SA, Piccioni F, Ott CJ, Leshchiner I, Johannessen CM, Doench J, Mootha VK, Getz G, Wu CJ. Guièze R, et al. Among authors: aygun o. Cancer Cell. 2019 Oct 14;36(4):369-384.e13. doi: 10.1016/j.ccell.2019.08.005. Epub 2019 Sep 19. Cancer Cell. 2019. PMID: 31543463 Free PMC article.
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins.
Udeshi ND, Pedram K, Svinkina T, Fereshetian S, Myers SA, Aygun O, Krug K, Clauser K, Ryan D, Ast T, Mootha VK, Ting AY, Carr SA. Udeshi ND, et al. Among authors: aygun o. Nat Methods. 2017 Dec;14(12):1167-1170. doi: 10.1038/nmeth.4465. Epub 2017 Oct 16. Nat Methods. 2017. PMID: 29039416 Free PMC article.
GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death.
Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, Greka A. Sieber J, et al. Among authors: aygun o. Cell Chem Biol. 2018 Feb 15;25(2):175-184.e4. doi: 10.1016/j.chembiol.2017.11.006. Epub 2017 Dec 14. Cell Chem Biol. 2018. PMID: 29249695 Free PMC article.
Multiomic Analysis of the UV-Induced DNA Damage Response.
Boeing S, Williamson L, Encheva V, Gori I, Saunders RE, Instrell R, Aygün O, Rodriguez-Martinez M, Weems JC, Kelly GP, Conaway JW, Conaway RC, Stewart A, Howell M, Snijders AP, Svejstrup JQ. Boeing S, et al. Among authors: aygun o. Cell Rep. 2016 May 17;15(7):1597-1610. doi: 10.1016/j.celrep.2016.04.047. Epub 2016 May 12. Cell Rep. 2016. PMID: 27184836 Free PMC article.
Direct inhibition of RNA polymerase II transcription by RECQL5.
Aygün O, Xu X, Liu Y, Takahashi H, Kong SE, Conaway RC, Conaway JW, Svejstrup JQ. Aygün O, et al. J Biol Chem. 2009 Aug 28;284(35):23197-203. doi: 10.1074/jbc.M109.015750. Epub 2009 Jul 1. J Biol Chem. 2009. PMID: 19570979 Free PMC article.
38 results