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PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS Jr, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP. Celada LJ, et al. Among authors: ayers gd. Sci Transl Med. 2018 Sep 26;10(460):eaar8356. doi: 10.1126/scitranslmed.aar8356. Sci Transl Med. 2018. PMID: 30257954 Free PMC article.
MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.
Vilgelm AE, Saleh N, Shattuck-Brandt R, Riemenschneider K, Slesur L, Chen SC, Johnson CA, Yang J, Blevins A, Yan C, Johnson DB, Al-Rohil RN, Halilovic E, Kauffmann RM, Kelley M, Ayers GD, Richmond A. Vilgelm AE, et al. Among authors: ayers gd. Sci Transl Med. 2019 Aug 14;11(505):eaav7171. doi: 10.1126/scitranslmed.aav7171. Sci Transl Med. 2019. PMID: 31413145 Free PMC article.
Efficacy of cetuximab in the treatment of Menetrier's disease.
Fiske WH, Tanksley J, Nam KT, Goldenring JR, Slebos RJ, Liebler DC, Abtahi AM, La Fleur B, Ayers GD, Lind CD, Washington MK, Coffey RJ. Fiske WH, et al. Among authors: ayers gd. Sci Transl Med. 2009 Nov 25;1(8):8ra18. doi: 10.1126/scitranslmed.3000320. Sci Transl Med. 2009. PMID: 20368185 Free PMC article. Clinical Trial.
SIX2 Effects on Wilms Tumor Biology.
Pierce J, Murphy AJ, Panzer A, de Caestecker C, Ayers GD, Neblett D, Saito-Diaz K, de Caestecker M, Lovvorn HN 3rd. Pierce J, et al. Among authors: ayers gd. Transl Oncol. 2014 Dec;7(6):800-11. doi: 10.1016/j.tranon.2014.09.005. Transl Oncol. 2014. PMID: 25500091 Free PMC article.
PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses.
Sai J, Owens P, Novitskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, Boothby M, Richmond A. Sai J, et al. Among authors: ayers gd. Clin Cancer Res. 2017 Jul 1;23(13):3371-3384. doi: 10.1158/1078-0432.CCR-16-2142. Epub 2016 Dec 21. Clin Cancer Res. 2017. PMID: 28003307 Free PMC article.
Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.
McKinley ET, Ayers GD, Smith RA, Saleh SA, Zhao P, Washington MK, Coffey RJ, Manning HC. McKinley ET, et al. Among authors: ayers gd. PLoS One. 2013;8(3):e58938. doi: 10.1371/journal.pone.0058938. Epub 2013 Mar 15. PLoS One. 2013. PMID: 23554961 Free PMC article.
124 results