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Application of in situ diffraction in high-throughput structure determination platforms.
Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA. Aller P, et al. Among authors: axford d. Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Methods Mol Biol. 2015. PMID: 25502203 Review.
Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.
Hausmann J, Christodoulou E, Kasiem M, De Marco V, van Meeteren LA, Moolenaar WH, Axford D, Owen RL, Evans G, Perrakis A. Hausmann J, et al. Among authors: axford d. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1130-5. doi: 10.1107/S1744309110032938. Epub 2010 Aug 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823545 Free PMC article.
High-speed crystal detection and characterization using a fast-readout detector.
Aishima J, Owen RL, Axford D, Shepherd E, Winter G, Levik K, Gibbons P, Ashton A, Evans G. Aishima J, et al. Among authors: axford d. Acta Crystallogr D Biol Crystallogr. 2010 Sep;66(Pt 9):1032-5. doi: 10.1107/S0907444910028192. Epub 2010 Aug 13. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20823554 Free PMC article.
The design of macromolecular crystallography diffraction experiments.
Evans G, Axford D, Owen RL. Evans G, et al. Among authors: axford d. Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):261-70. doi: 10.1107/S0907444911007608. Epub 2011 Mar 18. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21460444 Free PMC article.
Four complete turns of a curved 3₁₀-helix at atomic resolution: the crystal structure of the peptaibol trichovirin I-4A in a polar environment suggests a transition to α-helix for membrane function.
Gessmann R, Axford D, Owen RL, Brückner H, Petratos K. Gessmann R, et al. Among authors: axford d. Acta Crystallogr D Biol Crystallogr. 2012 Feb;68(Pt 2):109-16. doi: 10.1107/S090744491105133X. Epub 2012 Jan 6. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22281739
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Wang X, Peng W, Ren J, Hu Z, Xu J, Lou Z, Li X, Yin W, Shen X, Porta C, Walter TS, Evans G, Axford D, Owen R, Rowlands DJ, Wang J, Stuart DI, Fry EE, Rao Z. Wang X, et al. Among authors: axford d. Nat Struct Mol Biol. 2012 Mar 4;19(4):424-9. doi: 10.1038/nsmb.2255. Nat Struct Mol Biol. 2012. PMID: 22388738 Free PMC article.
In situ macromolecular crystallography using microbeams.
Axford D, Owen RL, Aishima J, Foadi J, Morgan AW, Robinson JI, Nettleship JE, Owens RJ, Moraes I, Fry EE, Grimes JM, Harlos K, Kotecha A, Ren J, Sutton G, Walter TS, Stuart DI, Evans G. Axford D, et al. Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):592-600. doi: 10.1107/S0907444912006749. Epub 2012 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22525757 Free PMC article.
Outrunning free radicals in room-temperature macromolecular crystallography.
Owen RL, Axford D, Nettleship JE, Owens RJ, Robinson JI, Morgan AW, Doré AS, Lebon G, Tate CG, Fry EE, Ren J, Stuart DI, Evans G. Owen RL, et al. Among authors: axford d. Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):810-8. doi: 10.1107/S0907444912012553. Epub 2012 Jun 15. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22751666 Free PMC article.
Picornavirus uncoating intermediate captured in atomic detail.
Ren J, Wang X, Hu Z, Gao Q, Sun Y, Li X, Porta C, Walter TS, Gilbert RJ, Zhao Y, Axford D, Williams M, McAuley K, Rowlands DJ, Yin W, Wang J, Stuart DI, Rao Z, Fry EE. Ren J, et al. Among authors: axford d. Nat Commun. 2013;4:1929. doi: 10.1038/ncomms2889. Nat Commun. 2013. PMID: 23728514 Free PMC article.
70 results