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Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances DNA damage.
Nappi A, Miro C, Pezone A, Tramontano A, Di Cicco E, Sagliocchi S, Cicatiello AG, Murolo M, Torabinejad S, Abbotto E, Caiazzo G, Raia M, Stornaiuolo M, Antonini D, Fabbrocini G, Salvatore D, Avvedimento VE, Dentice M. Nappi A, et al. Among authors: avvedimento ve. Nat Commun. 2023 Mar 4;14(1):1244. doi: 10.1038/s41467-023-36755-y. Nat Commun. 2023. PMID: 36871014 Free PMC article.
Selective demethylation of two CpG sites causes postnatal activation of the Dao gene and consequent removal of D-serine within the mouse cerebellum.
Cuomo M, Keller S, Punzo D, Nuzzo T, Affinito O, Coretti L, Carella M, de Rosa V, Florio E, Boscia F, Avvedimento VE, Cocozza S, Errico F, Usiello A, Chiariotti L. Cuomo M, et al. Among authors: avvedimento ve. Clin Epigenetics. 2019 Oct 28;11(1):149. doi: 10.1186/s13148-019-0732-z. Clin Epigenetics. 2019. PMID: 31661019 Free PMC article.
Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene.
Florio E, Keller S, Coretti L, Affinito O, Scala G, Errico F, Fico A, Boscia F, Sisalli MJ, Reccia MG, Miele G, Monticelli A, Scorziello A, Lembo F, Colucci-D'Amato L, Minchiotti G, Avvedimento VE, Usiello A, Cocozza S, Chiariotti L. Florio E, et al. Among authors: avvedimento ve. Epigenetics. 2017 Jan 2;12(1):41-54. doi: 10.1080/15592294.2016.1260211. Epub 2016 Nov 18. Epigenetics. 2017. PMID: 27858532 Free PMC article.
Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.
Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L. Carrella D, et al. Among authors: avvedimento ve. Oncotarget. 2016 Sep 13;7(37):58743-58758. doi: 10.18632/oncotarget.11318. Oncotarget. 2016. PMID: 27542212 Free PMC article.
55 results