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Rapid diagnostic test: a critical need for outbreak preparedness and response for high priority pathogens.
Yimer SA, Booij BB, Tobert G, Hebbeler A, Oloo P, Brangel P, L'Azou Jackson M, Jarman R, Craig D, Avumegah MS, Mandi H, Endy T, Wooden S, Clark C, Bernasconi V, Shurtleff A, Kristiansen PA. Yimer SA, et al. Among authors: avumegah ms. BMJ Glob Health. 2024 Apr 30;9(4):e014386. doi: 10.1136/bmjgh-2023-014386. BMJ Glob Health. 2024. PMID: 38688565 Free PMC article. Review.
Availability and use of Standards in vaccine development.
Avumegah MS, Mattiuzzo G, Särnefält A, Page M, Makar K, Lathey J, Kim J, Yimer SA, Craig D, Knezevic I, Bernasconi V, Kristiansen PA, Kromann I. Avumegah MS, et al. NPJ Vaccines. 2023 Jun 30;8(1):95. doi: 10.1038/s41541-023-00692-0. NPJ Vaccines. 2023. PMID: 37391580 Free PMC article. Review.
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein.
Albornoz EA, Amarilla AA, Modhiran N, Parker S, Li XX, Wijesundara DK, Aguado J, Zamora AP, McMillan CLD, Liang B, Peng NYG, Sng JDJ, Saima FT, Fung JN, Lee JD, Paramitha D, Parry R, Avumegah MS, Isaacs A, Lo MW, Miranda-Chacon Z, Bradshaw D, Salinas-Rebolledo C, Rajapakse NW, Wolvetang EJ, Munro TP, Rojas-Fernandez A, Young PR, Stacey KJ, Khromykh AA, Chappell KJ, Watterson D, Woodruff TM. Albornoz EA, et al. Among authors: avumegah ms. Mol Psychiatry. 2023 Jul;28(7):2878-2893. doi: 10.1038/s41380-022-01831-0. Epub 2022 Nov 1. Mol Psychiatry. 2023. PMID: 36316366 Free PMC article.
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial.
Chappell KJ, Mordant FL, Li Z, Wijesundara DK, Ellenberg P, Lackenby JA, Cheung STM, Modhiran N, Avumegah MS, Henderson CL, Hoger K, Griffin P, Bennet J, Hensen L, Zhang W, Nguyen THO, Marrero-Hernandez S, Selva KJ, Chung AW, Tran MH, Tapley P, Barnes J, Reading PC, Nicholson S, Corby S, Holgate T, Wines BD, Hogarth PM, Kedzierska K, Purcell DFJ, Ranasinghe C, Subbarao K, Watterson D, Young PR, Munro TP. Chappell KJ, et al. Among authors: avumegah ms. Lancet Infect Dis. 2021 Oct;21(10):1383-1394. doi: 10.1016/S1473-3099(21)00200-0. Epub 2021 Apr 19. Lancet Infect Dis. 2021. PMID: 33887208 Free PMC article. Clinical Trial.
Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2.
Watterson D, Wijesundara DK, Modhiran N, Mordant FL, Li Z, Avumegah MS, McMillan CL, Lackenby J, Guilfoyle K, van Amerongen G, Stittelaar K, Cheung ST, Bibby S, Daleris M, Hoger K, Gillard M, Radunz E, Jones ML, Hughes K, Hughes B, Goh J, Edwards D, Scoble J, Pearce L, Kowalczyk L, Phan T, La M, Lu L, Pham T, Zhou Q, Brockman DA, Morgan SJ, Lau C, Tran MH, Tapley P, Villalón-Letelier F, Barnes J, Young A, Jaberolansar N, Scott CA, Isaacs A, Amarilla AA, Khromykh AA, van den Brand JM, Reading PC, Ranasinghe C, Subbarao K, Munro TP, Young PR, Chappell KJ. Watterson D, et al. Among authors: avumegah ms. Clin Transl Immunology. 2021 Apr 5;10(4):e1269. doi: 10.1002/cti2.1269. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33841880 Free PMC article.
Rapid Response Subunit Vaccine Design in the Absence of Structural Information.
Wijesundara DK, Avumegah MS, Lackenby J, Modhiran N, Isaacs A, Young PR, Watterson D, Chappell KJ. Wijesundara DK, et al. Among authors: avumegah ms. Front Immunol. 2020 Nov 4;11:592370. doi: 10.3389/fimmu.2020.592370. eCollection 2020. Front Immunol. 2020. PMID: 33250897 Free PMC article.