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Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.
Harlow ML, Maloney N, Roland J, Guillen Navarro MJ, Easton MK, Kitchen-Goosen SM, Boguslawski EA, Madaj ZB, Johnson BK, Bowman MJ, D'Incalci M, Winn ME, Turner L, Hostetter G, Galmarini CM, Aviles PM, Grohar PJ. Harlow ML, et al. Cancer Res. 2016 Nov 15;76(22):6657-6668. doi: 10.1158/0008-5472.CAN-16-0568. Epub 2016 Oct 3. Cancer Res. 2016. PMID: 27697767 Free PMC article.
Evaluation of the Preclinical Efficacy of Lurbinectedin in Malignant Pleural Mesothelioma.
Anobile DP, Bironzo P, Picca F, Lingua MF, Morena D, Righi L, Napoli F, Papotti MG, Pittaro A, Di Nicolantonio F, Gigliotti C, Bussolino F, Comunanza V, Guerrera F, Sandri A, Leo F, Libener R, Aviles P, Novello S, Taulli R, Scagliotti GV, Riganti C. Anobile DP, et al. Among authors: aviles p. Cancers (Basel). 2021 May 12;13(10):2332. doi: 10.3390/cancers13102332. Cancers (Basel). 2021. PMID: 34066159 Free PMC article.
PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity.
Leal JF, Martínez-Díez M, García-Hernández V, Moneo V, Domingo A, Bueren-Calabuig JA, Negri A, Gago F, Guillén-Navarro MJ, Avilés P, Cuevas C, García-Fernández LF, Galmarini CM. Leal JF, et al. Among authors: aviles p. Br J Pharmacol. 2010 Nov;161(5):1099-110. doi: 10.1111/j.1476-5381.2010.00945.x. Br J Pharmacol. 2010. PMID: 20977459 Free PMC article.
Quantitative analysis of Variolin analog (PM01218) in mouse and rat plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Yin J, Aviles P, Ly C, Lee W, Guillen MJ, Munt S, Cuevas C, Faircloth G. Yin J, et al. Among authors: aviles p. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Mar 7;832(2):268-73. doi: 10.1016/j.jchromb.2006.01.027. Epub 2006 Feb 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16497567
Molecular pharmacology and antitumor activity of Zalypsis in several human cancer cell lines.
Leal JF, García-Hernández V, Moneo V, Domingo A, Bueren-Calabuig JA, Negri A, Gago F, Guillén-Navarro MJ, Avilés P, Cuevas C, García-Fernández LF, Galmarini CM. Leal JF, et al. Among authors: aviles p. Biochem Pharmacol. 2009 Jul 15;78(2):162-70. doi: 10.1016/j.bcp.2009.04.003. Epub 2009 Apr 11. Biochem Pharmacol. 2009. PMID: 19427997
67 results