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Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species.
González-Lizárraga F, Socías SB, Ávila CL, Torres-Bugeau CM, Barbosa LR, Binolfi A, Sepúlveda-Díaz JE, Del-Bel E, Fernandez CO, Papy-Garcia D, Itri R, Raisman-Vozari R, Chehín RN. González-Lizárraga F, et al. Among authors: avila cl. Sci Rep. 2017 Feb 3;7:41755. doi: 10.1038/srep41755. Sci Rep. 2017. PMID: 28155912 Free PMC article.
Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation.
Torres-Bugeau CM, Ávila CL, Raisman-Vozari R, Papy-Garcia D, Itri R, Barbosa LR, Cortez LM, Sim VL, Chehín RN. Torres-Bugeau CM, et al. Among authors: avila cl. J Biol Chem. 2012 Jan 20;287(4):2398-409. doi: 10.1074/jbc.M111.303503. Epub 2011 Dec 1. J Biol Chem. 2012. PMID: 22134915 Free PMC article.
Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound.
Tomas-Grau R, González-Lizárraga F, Ploper D, Avila CL, Socías SB, Besnault P, Tourville A, Mella RM, Villacé P, Salado C, Rose C, Seon-Méniel B, Brunel JM, Ferrié L, Raisman-Vozari R, Michel PP, Figadère B, Chehín R. Tomas-Grau R, et al. Among authors: avila cl. Cells. 2022 Sep 4;11(17):2759. doi: 10.3390/cells11172759. Cells. 2022. PMID: 36078167 Free PMC article.
48 results