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626 results

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The gut microbiota influences skeletal muscle mass and function in mice.
Lahiri S, Kim H, Garcia-Perez I, Reza MM, Martin KA, Kundu P, Cox LM, Selkrig J, Posma JM, Zhang H, Padmanabhan P, Moret C, Gulyás B, Blaser MJ, Auwerx J, Holmes E, Nicholson J, Wahli W, Pettersson S. Lahiri S, et al. Among authors: auwerx j. Sci Transl Med. 2019 Jul 24;11(502):eaan5662. doi: 10.1126/scitranslmed.aan5662. Sci Transl Med. 2019. PMID: 31341063 Free PMC article.
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.
Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J. Pirinen E, et al. Among authors: auwerx j. Cell Metab. 2014 Jun 3;19(6):1034-41. doi: 10.1016/j.cmet.2014.04.002. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814482 Free PMC article.
Protein acetylation in metabolism - metabolites and cofactors.
Menzies KJ, Zhang H, Katsyuba E, Auwerx J. Menzies KJ, et al. Among authors: auwerx j. Nat Rev Endocrinol. 2016 Jan;12(1):43-60. doi: 10.1038/nrendo.2015.181. Epub 2015 Oct 27. Nat Rev Endocrinol. 2016. PMID: 26503676 Review.
NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation.
Ryu D, Zhang H, Ropelle ER, Sorrentino V, Mázala DA, Mouchiroud L, Marshall PL, Campbell MD, Ali AS, Knowels GM, Bellemin S, Iyer SR, Wang X, Gariani K, Sauve AA, Cantó C, Conley KE, Walter L, Lovering RM, Chin ER, Jasmin BJ, Marcinek DJ, Menzies KJ, Auwerx J. Ryu D, et al. Among authors: auwerx j. Sci Transl Med. 2016 Oct 19;8(361):361ra139. doi: 10.1126/scitranslmed.aaf5504. Sci Transl Med. 2016. PMID: 27798264 Free PMC article.
The role of mitochondria in stem cell fate and aging.
Zhang H, Menzies KJ, Auwerx J. Zhang H, et al. Among authors: auwerx j. Development. 2018 Apr 13;145(8):dev143420. doi: 10.1242/dev.143420. Development. 2018. PMID: 29654217 Free PMC article. Review.
Long noncoding RNA SNHG12 integrates a DNA-PK-mediated DNA damage response and vascular senescence.
Haemmig S, Yang D, Sun X, Das D, Ghaffari S, Molinaro R, Chen L, Deng Y, Freeman D, Moullan N, Tesmenitsky Y, Wara AKMK, Simion V, Shvartz E, Lee JF, Yang T, Sukova G, Marto JA, Stone PH, Lee WL, Auwerx J, Libby P, Feinberg MW. Haemmig S, et al. Among authors: auwerx j. Sci Transl Med. 2020 Feb 19;12(531):eaaw1868. doi: 10.1126/scitranslmed.aaw1868. Sci Transl Med. 2020. PMID: 32075942
PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Rombold O, Agar NYR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. Yoon H, et al. Among authors: auwerx j. Cell Metab. 2020 Aug 4;32(2):215-228.e7. doi: 10.1016/j.cmet.2020.06.017. Epub 2020 Jul 13. Cell Metab. 2020. PMID: 32663458 Free PMC article.
626 results