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Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease: The BEAMS Randomized Clinical Trial.
Ekström M, Ferreira D, Chang S, Louw S, Johnson MJ, Eckert DJ, Fazekas B, Clark KJ, Agar MR, Currow DC; Australian National Palliative Care Clinical Studies Collaborative. Ekström M, et al. JAMA. 2022 Nov 22;328(20):2022-2032. doi: 10.1001/jama.2022.20206. JAMA. 2022. PMID: 36413230 Free PMC article. Clinical Trial.
Regular, sustained-release morphine for chronic breathlessness: a multicentre, double-blind, randomised, placebo-controlled trial.
Currow D, Louw S, McCloud P, Fazekas B, Plummer J, McDonald CF, Agar M, Clark K, McCaffrey N, Ekström MP; Australian National Palliative Care Clinical Studies Collaborative (PaCCSC). Currow D, et al. Thorax. 2020 Jan;75(1):50-56. doi: 10.1136/thoraxjnl-2019-213681. Epub 2019 Sep 26. Thorax. 2020. PMID: 31558624 Clinical Trial.
Controlled-Release Oxycodone vs. Placebo in the Treatment of Chronic Breathlessness-A Multisite Randomized Placebo Controlled Trial.
Ferreira DH, Louw S, McCloud P, Fazekas B, McDonald CF, Agar MR, Clark K, McCaffrey N, Ekström M, Currow DC; Australian National Palliative Care Clinical Studies Collaborative (PaCCSC). Ferreira DH, et al. J Pain Symptom Manage. 2020 Mar;59(3):581-589. doi: 10.1016/j.jpainsymman.2019.10.017. Epub 2019 Oct 23. J Pain Symptom Manage. 2020. PMID: 31655189 Free article. Clinical Trial.
Study protocol: a phase III randomised, double-blind, parallel arm, stratified, block randomised, placebo-controlled trial investigating the clinical effect and cost-effectiveness of sertraline for the palliative relief of breathlessness in people with chronic breathlessness.
Watts GJ, Clark K, Agar M, Davidson PM, McDonald C, Lam LT, Sajkov D, McCaffrey N, Doogue M, Abernethy AP, Currow DC; Australian national Palliative Care Clinical Studies Collaborative (PaCCSC). Watts GJ, et al. BMJ Open. 2016 Nov 29;6(11):e013177. doi: 10.1136/bmjopen-2016-013177. BMJ Open. 2016. PMID: 27899400 Free PMC article. Clinical Trial.
A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.
Currow D, Watts GJ, Johnson M, McDonald CF, Miners JO, Somogyi AA, Denehy L, McCaffrey N, Eckert DJ, McCloud P, Louw S, Lam L, Greene A, Fazekas B, Clark KC, Fong K, Agar MR, Joshi R, Kilbreath S, Ferreira D, Ekström M; Australian national Palliative Care Clinical Studies Collaborative (PaCCSC). Currow D, et al. BMJ Open. 2017 Jul 17;7(7):e018100. doi: 10.1136/bmjopen-2017-018100. BMJ Open. 2017. PMID: 28716797 Free PMC article. Clinical Trial.