Austen BM - Search Results

1

The elusive nature and diagnostics of misfolded Aβ oligomers.

Cerasoli E, Ryadnov MG, Austen BM. Cerasoli E, et al. Among authors: austen bm. Front Chem. 2015 Mar 19;3:17. doi: 10.3389/fchem.2015.00017. eCollection 2015. Front Chem. 2015. PMID: 25853119 Free PMC article. Review.

2

Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2.

Russell CL, Semerdjieva S, Empson RM, Austen BM, Beesley PW, Alifragis P. Russell CL, et al. Among authors: austen bm. PLoS One. 2012;7(8):e43201. doi: 10.1371/journal.pone.0043201. Epub 2012 Aug 15. PLoS One. 2012. PMID: 22905234 Free PMC article.

3

The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors.

Parsons RB, Aravindan S, Kadampeswaran A, Evans EA, Sandhu KK, Levy ER, Thomas MG, Austen BM, Ramsden DB. Parsons RB, et al. Among authors: austen bm. Biochem J. 2011 May 15;436(1):145-55. doi: 10.1042/BJ20101685. Biochem J. 2011. PMID: 21352099

4

Development of retro-inverso peptides as anti-aggregation drugs for β-amyloid in Alzheimer's disease.

Matharu B, El-Agnaf O, Razvi A, Austen BM. Matharu B, et al. Among authors: austen bm. Peptides. 2010 Oct;31(10):1866-72. doi: 10.1016/j.peptides.2010.06.033. Epub 2010 Jul 13. Peptides. 2010. PMID: 20633587

5

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

Austen BM, Paleologou KE, Ali SA, Qureshi MM, Allsop D, El-Agnaf OM. Austen BM, et al. Biochemistry. 2008 Feb 19;47(7):1984-92. doi: 10.1021/bi701415b. Epub 2008 Jan 12. Biochemistry. 2008. PMID: 18189413

6

Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.

Parsons RB, Austen BM. Parsons RB, et al. Among authors: austen bm. Biochem Soc Trans. 2007 Nov;35(Pt 5):974-9. doi: 10.1042/BST0350974. Biochem Soc Trans. 2007. PMID: 17956258 Review.

7

Regulation of the lipidation of beta-secretase by statins.

Parsons RB, Farrant JK, Price GC, Subramaniam D, Austen BM. Parsons RB, et al. Among authors: austen bm. Biochem Soc Trans. 2007 Jun;35(Pt 3):577-82. doi: 10.1042/BST0350577. Biochem Soc Trans. 2007. PMID: 17511656 Review.

8

A specific inhibitor of cholesterol biosynthesis, BM15.766, reduces the expression of beta-secretase and the production of amyloid-beta in vitro.

Parsons RB, Subramaniam D, Austen BM. Parsons RB, et al. Among authors: austen bm. J Neurochem. 2007 Aug;102(4):1276-91. doi: 10.1111/j.1471-4159.2007.04619.x. Epub 2007 Apr 30. J Neurochem. 2007. PMID: 17472704 Free article.

9

Statins inhibit the dimerization of beta-secretase via both isoprenoid- and cholesterol-mediated mechanisms.

Parsons RB, Price GC, Farrant JK, Subramaniam D, Adeagbo-Sheikh J, Austen BM. Parsons RB, et al. Among authors: austen bm. Biochem J. 2006 Oct 15;399(2):205-14. doi: 10.1042/BJ20060655. Biochem J. 2006. PMID: 16803455 Free PMC article.

10

Structure and neurotoxicity of novel amyloids derived from the BRI gene.

Gibson G, El-Agnaf OM, Anwar Z, Sidera C, Isbister A, Austen BM. Gibson G, et al. Among authors: austen bm. Biochem Soc Trans. 2005 Nov;33(Pt 5):1111-2. doi: 10.1042/BST20051111. Biochem Soc Trans. 2005. PMID: 16246057

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