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A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43.
Nanayakkara M, Kosova R, Lania G, Sarno M, Gaito A, Galatola M, Greco L, Cuomo M, Troncone R, Auricchio S, Auricchio R, Barone MV. Nanayakkara M, et al. Among authors: auricchio r, auricchio s. PLoS One. 2013 Nov 22;8(11):e79763. doi: 10.1371/journal.pone.0079763. eCollection 2013. PLoS One. 2013. PMID: 24278174 Free PMC article.
P31-43, an undigested gliadin peptide, mimics and enhances the innate immune response to viruses and interferes with endocytic trafficking: a role in celiac disease.
Nanayakkara M, Lania G, Maglio M, Auricchio R, De Musis C, Discepolo V, Miele E, Jabri B, Troncone R, Auricchio S, Barone MV. Nanayakkara M, et al. Among authors: auricchio r, auricchio s. Sci Rep. 2018 Jul 17;8(1):10821. doi: 10.1038/s41598-018-28830-y. Sci Rep. 2018. PMID: 30018339 Free PMC article.
Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin.
Lania G, Nanayakkara M, Maglio M, Auricchio R, Porpora M, Conte M, De Matteis MA, Rizzo R, Luini A, Discepolo V, Troncone R, Auricchio S, Barone MV. Lania G, et al. Among authors: auricchio r, auricchio s. Commun Biol. 2019 May 20;2:190. doi: 10.1038/s42003-019-0443-1. eCollection 2019. Commun Biol. 2019. PMID: 31123714 Free PMC article.
343 results