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Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.
Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T. Smiljanovic B, et al. Among authors: aupperle k. Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30. Ann Rheum Dis. 2018. PMID: 29191820 Free PMC article.
Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation.
Smiljanovic B, Grützkau A, Sörensen T, Grün JR, Vogl T, Bonin M, Schendel P, Stuhlmüller B, Claussnitzer A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Radbruch A, Burmester GR, Häupl T. Smiljanovic B, et al. Among authors: aupperle k. Sci Rep. 2020 May 13;10(1):7907. doi: 10.1038/s41598-020-64431-4. Sci Rep. 2020. PMID: 32404914 Free PMC article.
Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response.
Enghard P, Rieder C, Kopetschke K, Klocke JR, Undeutsch R, Biesen R, Dragun D, Gollasch M, Schneider U, Aupperle K, Humrich JY, Hiepe F, Backhaus M, Radbruch AH, Burmester GR, Riemekasten G. Enghard P, et al. Among authors: aupperle k. Ann Rheum Dis. 2014 Jan;73(1):277-83. doi: 10.1136/annrheumdis-2012-202784. Epub 2013 Mar 8. Ann Rheum Dis. 2014. PMID: 23475982 Clinical Trial.
Jun N-terminal kinase in rheumatoid arthritis.
Han Z, Boyle DL, Aupperle KR, Bennett B, Manning AM, Firestein GS. Han Z, et al. Among authors: aupperle kr. J Pharmacol Exp Ther. 1999 Oct;291(1):124-30. J Pharmacol Exp Ther. 1999. PMID: 10490895
15 results