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Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Abbott KL, Ali A, Casalena D, Do BT, Ferreira R, Cheah JH, Soule CK, Deik A, Kunchok T, Schmidt DR, Renner S, Honeder SE, Wu M, Chan SH, Tseyang T, Stoltzfus AT, Michel SLJ, Greaves D, Hsu PP, Ng CW, Zhang CJ, Farsidjani A, Kent JR, Madariaga MLL, Gramatikov IMT, Matheson NJ, Lewis CA, Clish CB, Rees MG, Roth JA, Griner LM, Muir A, Auld DS, Vander Heiden MG. Abbott KL, et al. Among authors: auld ds. Cell Chem Biol. 2023 Sep 21;30(9):1156-1168.e7. doi: 10.1016/j.chembiol.2023.08.007. Epub 2023 Sep 8. Cell Chem Biol. 2023. PMID: 37689063
SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.
L Vu KA, Kumari K, Liu BH, Gao C, Li F, Tang JP, Maddalo D, Auld DS, Casalena DE, Tian X, Liu M, Bassal MA, Moein S, Iakovleva V, Tan JL, Stein AJ, Zhou Q, Fischer PD, Sigua LH, Qi J, Arthanari H, Tenen DG, Chai L. L Vu KA, et al. Among authors: auld ds. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.548071. doi: 10.1101/2023.07.07.548071. bioRxiv. 2023. PMID: 37461690 Free PMC article. Preprint.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Abbott KL, Ali A, Casalena D, Do BT, Ferreira R, Cheah JH, Soule CK, Deik A, Kunchok T, Schmidt DR, Renner S, Honeder SE, Wu M, Chan SH, Tseyang T, Greaves D, Hsu PP, Ng CW, Zhang CJ, Farsidjani A, Gramatikov IMT, Matheson NJ, Lewis CA, Clish CB, Rees MG, Roth JA, Griner LM, Muir A, Auld DS, Heiden MGV. Abbott KL, et al. Among authors: auld ds. bioRxiv [Preprint]. 2023 Feb 27:2023.02.25.529972. doi: 10.1101/2023.02.25.529972. bioRxiv. 2023. PMID: 36909640 Free PMC article. Updated. Preprint.
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK.
Tan C, Ginzberg MB, Webster R, Iyengar S, Liu S, Papadopoli D, Concannon J, Wang Y, Auld DS, Jenkins JL, Rost H, Topisirovic I, Hilfinger A, Derry WB, Patel N, Kafri R. Tan C, et al. Among authors: auld ds. Dev Cell. 2021 Jun 21;56(12):1756-1769.e7. doi: 10.1016/j.devcel.2021.04.030. Epub 2021 May 21. Dev Cell. 2021. PMID: 34022133 Free article.
Nuisance compounds in cellular assays.
Dahlin JL, Auld DS, Rothenaigner I, Haney S, Sexton JZ, Nissink JWM, Walsh J, Lee JA, Strelow JM, Willard FS, Ferrins L, Baell JB, Walters MA, Hua BK, Hadian K, Wagner BK. Dahlin JL, et al. Among authors: auld ds. Cell Chem Biol. 2021 Mar 18;28(3):356-370. doi: 10.1016/j.chembiol.2021.01.021. Epub 2021 Feb 15. Cell Chem Biol. 2021. PMID: 33592188 Free PMC article. Review.
Advancements in Assay Technologies and Strategies to Enable Drug Discovery.
Busby SA, Carbonneau S, Concannon J, Dumelin CE, Lee Y, Numao S, Renaud N, Smith TM, Auld DS. Busby SA, et al. Among authors: auld ds. ACS Chem Biol. 2020 Oct 16;15(10):2636-2648. doi: 10.1021/acschembio.0c00495. Epub 2020 Sep 18. ACS Chem Biol. 2020. PMID: 32880443 Review.
213 results