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Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions.
Canas PM, Porciúncula LO, Simões AP, Augusto E, Silva HB, Machado NJ, Gonçalves N, Alfaro TM, Gonçalves FQ, Araújo IM, Real JI, Coelho JE, Andrade GM, Almeida RD, Chen JF, Köfalvi A, Agostinho P, Cunha RA. Canas PM, et al. Among authors: augusto e. eNeuro. 2018 Dec 26;5(6):ENEURO.0385-18.2018. doi: 10.1523/ENEURO.0385-18.2018. eCollection 2018 Nov-Dec. eNeuro. 2018. PMID: 30627646 Free PMC article.
Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory.
Li P, Rial D, Canas PM, Yoo JH, Li W, Zhou X, Wang Y, van Westen GJ, Payen MP, Augusto E, Gonçalves N, Tomé AR, Li Z, Wu Z, Hou X, Zhou Y, IJzerman AP, Boyden ES, Cunha RA, Qu J, Chen JF. Li P, et al. Among authors: augusto e. Mol Psychiatry. 2015 Nov;20(11):1339-49. doi: 10.1038/mp.2014.182. Epub 2015 Feb 17. Mol Psychiatry. 2015. PMID: 25687775 Free PMC article.
46 results