Aubrecht J - Search Results

1

New and emerging technologies for genetic toxicity testing.

Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. Lynch AM, et al. Among authors: aubrecht j. Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Environ Mol Mutagen. 2011. PMID: 20740635 Review.

2

Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment.

Ku WW, Aubrecht J, Mauthe RJ, Schiestl RH, Fornace AJ Jr. Ku WW, et al. Among authors: aubrecht j. Toxicol Sci. 2007 Sep;99(1):20-5. doi: 10.1093/toxsci/kfm147. Epub 2007 Jun 4. Toxicol Sci. 2007. PMID: 17548889

3

Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells.

Li HH, Hyduke DR, Chen R, Heard P, Yauk CL, Aubrecht J, Fornace AJ Jr. Li HH, et al. Among authors: aubrecht j. Environ Mol Mutagen. 2015 Jul;56(6):505-19. doi: 10.1002/em.21941. Epub 2015 Mar 2. Environ Mol Mutagen. 2015. PMID: 25733355 Free PMC article.

4

Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9.

Yauk CL, Buick JK, Williams A, Swartz CD, Recio L, Li HH, Fornace AJ Jr, Thomson EM, Aubrecht J. Yauk CL, et al. Among authors: aubrecht j. Environ Mol Mutagen. 2016 May;57(4):243-60. doi: 10.1002/em.22004. Epub 2016 Mar 4. Environ Mol Mutagen. 2016. PMID: 26946220 Free PMC article.

5

Toxicogenomics: overview and potential applications for the study of non-covalent DNA interacting chemicals.

Li HH, Aubrecht J, Fornace AJ Jr. Li HH, et al. Among authors: aubrecht j. Mutat Res. 2007 Oct 1;623(1-2):98-108. doi: 10.1016/j.mrfmmm.2007.03.013. Epub 2007 Apr 21. Mutat Res. 2007. PMID: 17548094 Review.

6

Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.

Buick JK, Moffat I, Williams A, Swartz CD, Recio L, Hyduke DR, Li HH, Fornace AJ Jr, Aubrecht J, Yauk CL. Buick JK, et al. Among authors: aubrecht j. Environ Mol Mutagen. 2015 Jul;56(6):520-34. doi: 10.1002/em.21940. Epub 2015 Mar 2. Environ Mol Mutagen. 2015. PMID: 25733247 Free PMC article.

7

Assessment of the performance of the TGx-DDI biomarker to detect DNA damage-inducing agents using quantitative RT-PCR in TK6 cells.

Cho E, Buick JK, Williams A, Chen R, Li HH, Corton JC, Fornace AJ Jr, Aubrecht J, Yauk CL. Cho E, et al. Among authors: aubrecht j. Environ Mol Mutagen. 2019 Mar;60(2):122-133. doi: 10.1002/em.22257. Epub 2018 Nov 29. Environ Mol Mutagen. 2019. PMID: 30488505 Free PMC article.

8

Yeast DEL assay detects clastogens.

Kirpnick Z, Homiski M, Rubitski E, Repnevskaya M, Howlett N, Aubrecht J, Schiestl RH. Kirpnick Z, et al. Among authors: aubrecht j. Mutat Res. 2005 Apr 4;582(1-2):116-34. doi: 10.1016/j.mrgentox.2005.01.005. Mutat Res. 2005. PMID: 15781217

9

The utility of DNA microarrays for characterizing genotoxicity.

Newton RK, Aardema M, Aubrecht J. Newton RK, et al. Among authors: aubrecht j. Environ Health Perspect. 2004 Mar;112(4):420-2. doi: 10.1289/ehp.6709. Environ Health Perspect. 2004. PMID: 15033590 Free PMC article.

10

In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer.

Reliene R, Bishop AJ, Aubrecht J, Schiestl RH. Reliene R, et al. Among authors: aubrecht j. Methods Mol Biol. 2004;262:125-39. doi: 10.1385/1-59259-761-0:125. Methods Mol Biol. 2004. PMID: 14769959

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