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Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L, Alex A, Roubert C, Gardner M, Preston M, Smith DM, Ling Y, Roberts J, Cautain B, Upton A, Cooper CB, Serbina N, Tanvir Z, Mosior J, Ouerfelli O, Yang G, Gold BS, Rhee KY, Sacchettini JC, Fotouhi N, Aubé J, Nathan C. Singh A, et al. Among authors: aube j. Sci Adv. 2024 Mar 15;10(11):eadj6406. doi: 10.1126/sciadv.adj6406. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489355 Free PMC article.
MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth.
Cheng OJ, Lebish EJ, Jensen O, Jacenik D, Trivedi S, Cacioppo J, Aubé J, Beswick EJ, Leung DT. Cheng OJ, et al. Among authors: aube j. bioRxiv [Preprint]. 2024 Feb 2:2024.01.16.575894. doi: 10.1101/2024.01.16.575894. bioRxiv. 2024. PMID: 38293128 Free PMC article. Preprint.
SETD2 maintains nuclear lamina stability to safeguard the genome.
Khan A, Metts JM, Collins LC, Mills CA, Li K, Brademeyer AL, Bowman BM, Major MB, Aubé J, Herring LE, Davis IJ, Strahl BD. Khan A, et al. Among authors: aube j. bioRxiv [Preprint]. 2023 Sep 28:2023.09.28.560032. doi: 10.1101/2023.09.28.560032. bioRxiv. 2023. PMID: 37808753 Free PMC article. Preprint.
Mixed, nonclassical behavior in a classic allosteric protein.
Sapienza PJ, Bonin JP, Jinasena HPD, Li K, Dieckhaus H, Popov KI, Aubé J, Lee AL. Sapienza PJ, et al. Among authors: aube j. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2308338120. doi: 10.1073/pnas.2308338120. Epub 2023 Sep 11. Proc Natl Acad Sci U S A. 2023. PMID: 37695919 Free PMC article.
Type I interferons drive MAIT cell functions against bacterial pneumonia.
López-Rodríguez JC, Hancock SJ, Li K, Crotta S, Barrington C, Suárez-Bonnet A, Priestnall SL, Aubé J, Wack A, Klenerman P, Bengoechea JA, Barral P. López-Rodríguez JC, et al. Among authors: aube j. J Exp Med. 2023 Oct 2;220(10):e20230037. doi: 10.1084/jem.20230037. Epub 2023 Jul 26. J Exp Med. 2023. PMID: 37516912 Free PMC article.
277 results