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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Lippert AH, Paluch C, Gaglioni M, Vuong MT, McColl J, Jenkins E, Fellermeyer M, Clarke J, Sharma S, Moreira da Silva S, Akkaya B, Anzilotti C, Morgan SH, Jessup CF, Körbel M, Gileadi U, Leitner J, Knox R, Chirifu M, Huo J, Yu S, Ashman N, Lui Y, Wilkinson I, Attfield KE, Fugger L, Robertson NJ, Lynch CJ, Murray L, Steinberger P, Santos AM, Lee SF, Cornall RJ, Klenerman D, Davis SJ. Lippert AH, et al. Among authors: attfield ke. Immunity. 2024 Feb 13;57(2):256-270.e10. doi: 10.1016/j.immuni.2024.01.007. Immunity. 2024. PMID: 38354703 Free article.
The immunology of multiple sclerosis.
Attfield KE, Jensen LT, Kaufmann M, Friese MA, Fugger L. Attfield KE, et al. Nat Rev Immunol. 2022 Dec;22(12):734-750. doi: 10.1038/s41577-022-00718-z. Epub 2022 May 4. Nat Rev Immunol. 2022. PMID: 35508809 Review.
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, McVean G, Fugger L. Gregory AP, et al. Among authors: attfield ke. Nature. 2012 Aug 23;488(7412):508-511. doi: 10.1038/nature11307. Nature. 2012. PMID: 22801493 Free PMC article.
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L. Dendrou CA, et al. Among authors: attfield ke. Sci Transl Med. 2016 Nov 2;8(363):363ra149. doi: 10.1126/scitranslmed.aag1974. Sci Transl Med. 2016. PMID: 27807284 Free PMC article.
21 results