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The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.
Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ. Moon EJ, et al. Among authors: attardi ld. Nat Commun. 2021 Jul 14;12(1):4308. doi: 10.1038/s41467-021-24631-6. Nat Commun. 2021. PMID: 34262028 Free PMC article.
Genome-wide analysis of p53 under hypoxic conditions.
Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, Giaccia AJ. Hammond EM, et al. Among authors: attardi ld. Mol Cell Biol. 2006 May;26(9):3492-504. doi: 10.1128/MCB.26.9.3492-3504.2006. Mol Cell Biol. 2006. PMID: 16611991 Free PMC article.
Not all p53 gain-of-function mutants are created equal.
Mello SS, Attardi LD. Mello SS, et al. Among authors: attardi ld. Cell Death Differ. 2013 Jul;20(7):855-7. doi: 10.1038/cdd.2013.53. Cell Death Differ. 2013. PMID: 23749181 Free PMC article. No abstract available.
Unravelling mechanisms of p53-mediated tumour suppression.
Bieging KT, Mello SS, Attardi LD. Bieging KT, et al. Among authors: attardi ld. Nat Rev Cancer. 2014 May;14(5):359-70. doi: 10.1038/nrc3711. Epub 2014 Apr 17. Nat Rev Cancer. 2014. PMID: 24739573 Free PMC article.
The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development.
Van Nostrand JL, Brisac A, Mello SS, Jacobs SB, Luong R, Attardi LD. Van Nostrand JL, et al. Among authors: attardi ld. Cancer Discov. 2015 Jun;5(6):622-35. doi: 10.1158/2159-8290.CD-14-0921. Epub 2015 Mar 26. Cancer Discov. 2015. PMID: 25813352 Free PMC article.
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, Erkan M, Kleeff J, Sipos B, Sayles LC, Heikenwalder M, Heßmann E, Ellenrieder V, Esposito I, Jacks T, Bradner JE, Khatri P, Sweet-Cordero EA, Attardi LD, Schmid RM, Schneider G, Sage J, Siveke JT. Mazur PK, et al. Among authors: attardi ld. Nat Med. 2015 Oct;21(10):1163-71. doi: 10.1038/nm.3952. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390243 Free PMC article.
117 results