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Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis.
Cook DP, Cunha JPMCM, Martens PJ, Sassi G, Mancarella F, Ventriglia G, Sebastiani G, Vanherwegen AS, Atkinson MA, Van Huynegem K, Steidler L, Caluwaerts S, Rottiers P, Teyton L, Dotta F, Gysemans C, Mathieu C. Cook DP, et al. Among authors: atkinson ma. Front Immunol. 2020 Jun 9;11:1103. doi: 10.3389/fimmu.2020.01103. eCollection 2020. Front Immunol. 2020. PMID: 32582188 Free PMC article.
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.
Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, Gysemans C, Mathieu C. Takiishi T, et al. Among authors: atkinson ma. J Clin Invest. 2012 May;122(5):1717-25. doi: 10.1172/JCI60530. Epub 2012 Apr 9. J Clin Invest. 2012. PMID: 22484814 Free PMC article.
Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice.
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, Nepom G, Ehlers M, Staeva T, Garren H, Steinman L, Chan AC, von Herrath M. Sarikonda G, et al. PLoS One. 2013;8(2):e54712. doi: 10.1371/journal.pone.0054712. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405091 Free PMC article.
Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice.
Robert S, Gysemans C, Takiishi T, Korf H, Spagnuolo I, Sebastiani G, Van Huynegem K, Steidler L, Caluwaerts S, Demetter P, Wasserfall CH, Atkinson MA, Dotta F, Rottiers P, Van Belle TL, Mathieu C. Robert S, et al. Among authors: atkinson ma. Diabetes. 2014 Aug;63(8):2876-87. doi: 10.2337/db13-1236. Epub 2014 Mar 27. Diabetes. 2014. PMID: 24677716 Free article.
Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity.
Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Bonifacio E, et al. Among authors: atkinson ma. Diabetologia. 2017 Jan;60(1):35-38. doi: 10.1007/s00125-016-4144-8. Epub 2016 Oct 26. Diabetologia. 2017. PMID: 27785529 Free PMC article.
Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.
Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC. Babon JA, et al. Among authors: atkinson ma. Nat Med. 2016 Dec;22(12):1482-1487. doi: 10.1038/nm.4203. Epub 2016 Oct 31. Nat Med. 2016. PMID: 27798614 Free PMC article.
512 results