Aster JC - Search Results

1

Pharmacological disruption of the Notch transcription factor complex.

Lehal R, Zaric J, Vigolo M, Urech C, Frismantas V, Zangger N, Cao L, Berger A, Chicote I, Loubéry S, Choi SH, Koch U, Blacklow SC, Palmer HG, Bornhauser B, González-Gaitán M, Arsenijevic Y, Zoete V, Aster JC, Bourquin JP, Radtke F. Lehal R, et al. Among authors: aster jc. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16292-16301. doi: 10.1073/pnas.1922606117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601208 Free PMC article.

2

The folding and structural integrity of the first LIN-12 module of human Notch1 are calcium-dependent.

Aster JC, Simms WB, Zavala-Ruiz Z, Patriub V, North CL, Blacklow SC. Aster JC, et al. Biochemistry. 1999 Apr 13;38(15):4736-42. doi: 10.1021/bi982713o. Biochemistry. 1999. PMID: 10200161

3

Calcium depletion dissociates and activates heterodimeric notch receptors.

Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, Aster JC. Rand MD, et al. Among authors: aster jc. Mol Cell Biol. 2000 Mar;20(5):1825-35. doi: 10.1128/MCB.20.5.1825-1835.2000. Mol Cell Biol. 2000. PMID: 10669757 Free PMC article.

4

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD. Wu L, et al. Among authors: aster jc. Nat Genet. 2000 Dec;26(4):484-9. doi: 10.1038/82644. Nat Genet. 2000. PMID: 11101851

5

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation.

Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, Miele L, Aguet M, Radtke F, Dotto GP. Rangarajan A, et al. Among authors: aster jc. EMBO J. 2001 Jul 2;20(13):3427-36. doi: 10.1093/emboj/20.13.3427. EMBO J. 2001. PMID: 11432830 Free PMC article.

6

Notch signaling as a therapeutic target.

Nam Y, Aster JC, Blacklow SC. Nam Y, et al. Among authors: aster jc. Curr Opin Chem Biol. 2002 Aug;6(4):501-9. doi: 10.1016/s1367-5931(02)00346-0. Curr Opin Chem Biol. 2002. PMID: 12133727 Review.

7

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.

Weng AP, Nam Y, Wolfe MS, Pear WS, Griffin JD, Blacklow SC, Aster JC. Weng AP, et al. Among authors: aster jc. Mol Cell Biol. 2003 Jan;23(2):655-64. doi: 10.1128/MCB.23.2.655-664.2003. Mol Cell Biol. 2003. PMID: 12509463 Free PMC article.

8

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.

Nam Y, Weng AP, Aster JC, Blacklow SC. Nam Y, et al. Among authors: aster jc. J Biol Chem. 2003 Jun 6;278(23):21232-9. doi: 10.1074/jbc.M301567200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12644465 Free article.

9

Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1.

Vardar D, North CL, Sanchez-Irizarry C, Aster JC, Blacklow SC. Vardar D, et al. Among authors: aster jc. Biochemistry. 2003 Jun 17;42(23):7061-7. doi: 10.1021/bi034156y. Biochemistry. 2003. PMID: 12795601

10

Multiple niches for Notch in cancer: context is everything.

Weng AP, Aster JC. Weng AP, et al. Among authors: aster jc. Curr Opin Genet Dev. 2004 Feb;14(1):48-54. doi: 10.1016/j.gde.2003.11.004. Curr Opin Genet Dev. 2004. PMID: 15108805 Review.

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