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An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair.
Yan R, Cigliola V, Oonk KA, Petrover Z, DeLuca S, Wolfson DW, Vekstein A, Mendiola MA, Devlin G, Bishawi M, Gemberling MP, Sinha T, Sargent MA, York AJ, Shakked A, DeBenedittis P, Wendell DC, Ou J, Kang J, Goldman JA, Baht GS, Karra R, Williams AR, Bowles DE, Asokan A, Tzahor E, Gersbach CA, Molkentin JD, Bursac N, Black BL, Poss KD. Yan R, et al. Among authors: asokan a. Cell Stem Cell. 2023 Jan 5;30(1):96-111.e6. doi: 10.1016/j.stem.2022.11.012. Epub 2022 Dec 13. Cell Stem Cell. 2023. PMID: 36516837 Free PMC article.
An evolved AAV variant enables efficient genetic engineering of murine T cells.
Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY, Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A, Havlik LP, Pimentel H, Asokan A, Eyquem J. Nyberg WA, et al. Among authors: asokan a. Cell. 2023 Jan 19;186(2):446-460.e19. doi: 10.1016/j.cell.2022.12.022. Epub 2023 Jan 12. Cell. 2023. PMID: 36638795 Free PMC article.
Redirecting AAV vectors to extrahepatic tissues.
Asokan A, Shen S. Asokan A, et al. Mol Ther. 2023 Dec 6;31(12):3371-3375. doi: 10.1016/j.ymthe.2023.10.005. Epub 2023 Oct 6. Mol Ther. 2023. PMID: 37805712 Free article. Review.
Adeno-associated virus mediates gene transduction after static cold storage treatment in rodent lung transplantation.
Kesseli SJ, Krischak MK, Gao Q, Gonzalez T, Zhang M, Halpern SE, Kahan R, Song M, Huffman N, Xu H, Abraham N, Asokan A, Barbas AS, Hartwig MG. Kesseli SJ, et al. Among authors: asokan a. J Thorac Cardiovasc Surg. 2023 Jul;166(1):e38-e49. doi: 10.1016/j.jtcvs.2022.08.050. Epub 2022 Sep 24. J Thorac Cardiovasc Surg. 2023. PMID: 38501313 Free article.
203 results