Askham J - Search Results

1

Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.

Cubbon RM, Yuldasheva NY, Viswambharan H, Mercer BN, Baliga V, Stephen SL, Askham J, Sukumar P, Skromna A, Mughal RS, Walker AM, Bruns A, Bailey MA, Galloway S, Imrie H, Gage MC, Rakobowchuk M, Li J, Porter KE, Ponnambalam S, Wheatcroft SB, Beech DJ, Kearney MT. Cubbon RM, et al. Among authors: askham j. Stem Cells. 2014 Oct;32(10):2714-23. doi: 10.1002/stem.1766. Stem Cells. 2014. PMID: 24916783 Free article.

2

A novel p53 mutant found in iatrogenic urothelial cancers is dysfunctional and can be rescued by a second-site global suppressor mutation.

Odell AF, Odell LR, Askham JM, Alogheli H, Ponnambalam S, Hollstein M. Odell AF, et al. Among authors: askham jm. J Biol Chem. 2013 Jun 7;288(23):16704-16714. doi: 10.1074/jbc.M112.443168. Epub 2013 Apr 23. J Biol Chem. 2013. PMID: 23612969 Free PMC article.

3

AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K.

Askham JM, Platt F, Chambers PA, Snowden H, Taylor CF, Knowles MA. Askham JM, et al. Oncogene. 2010 Jan 7;29(1):150-5. doi: 10.1038/onc.2009.315. Epub 2009 Oct 5. Oncogene. 2010. PMID: 19802009

4

PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signaling and phenotypic outputs.

Ross RL, Askham JM, Knowles MA. Ross RL, et al. Among authors: askham jm. Oncogene. 2013 Feb 7;32(6):768-76. doi: 10.1038/onc.2012.87. Epub 2012 Mar 19. Oncogene. 2013. PMID: 22430209

5

How to become immortal: let MEFs count the ways.

Odell A, Askham J, Whibley C, Hollstein M. Odell A, et al. Among authors: askham j. Aging (Albany NY). 2010 Mar 31;2(3):160-5. doi: 10.18632/aging.100129. Aging (Albany NY). 2010. PMID: 20378935 Free PMC article. Review.

6

Bladder tumour-derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms.

Pymar LS, Platt FM, Askham JM, Morrison EE, Knowles MA. Pymar LS, et al. Hum Mol Genet. 2008 Jul 1;17(13):2006-17. doi: 10.1093/hmg/ddn098. Epub 2008 Apr 7. Hum Mol Genet. 2008. PMID: 18397877 Free PMC article.

7

EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle.

Morrison EE, Wardleworth BN, Askham JM, Markham AF, Meredith DM. Morrison EE, et al. Among authors: askham jm. Oncogene. 1998 Dec 31;17(26):3471-7. doi: 10.1038/sj.onc.1202247. Oncogene. 1998. PMID: 10030671

8

MCAK associates with EB1.

Lee T, Langford KJ, Askham JM, Brüning-Richardson A, Morrison EE. Lee T, et al. Among authors: askham jm. Oncogene. 2008 Apr 10;27(17):2494-500. doi: 10.1038/sj.onc.1210867. Epub 2007 Oct 29. Oncogene. 2008. PMID: 17968321

9

Regulation and function of the interaction between the APC tumour suppressor protein and EB1.

Askham JM, Moncur P, Markham AF, Morrison EE. Askham JM, et al. Oncogene. 2000 Apr 6;19(15):1950-8. doi: 10.1038/sj.onc.1203498. Oncogene. 2000. PMID: 10773885

10

Examination of actin and microtubule dependent APC localisations in living mammalian cells.

Langford KJ, Askham JM, Lee T, Adams M, Morrison EE. Langford KJ, et al. Among authors: askham jm. BMC Cell Biol. 2006 Jan 19;7:3. doi: 10.1186/1471-2121-7-3. BMC Cell Biol. 2006. PMID: 16423286 Free PMC article.

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